Evidence map›Paper›PMID 38513105›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Ferredoxin reduction by hydrogen with iron functions as an evolutionary precursor of flavin-based electron bifurcation.

Max Brabender, Delfina P Henriques Pereira, Natalia Mrnjavac, Manon Laura Schlikker, Zen-Ichiro Kimura, Jeerus Sucharitakul, Karl Kleinermanns, Harun Tüysüz, Wolfgang Buckel, Martina Preiner and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
10.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. FeNature communications · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Bacteria on steroids.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  12. Chemiosmotic ATP synthesis by minimal protocells.Cell reports. Physical science · 2025
    Article
  13. Review
  14. Article
  15. Review
  16. BioIron: Origin, Chemical Properties, and Biological Functions.Advances in experimental medicine and biology · 2025
    Review
  17. Review
  18. Chemical Antiquity in Metabolism.Accounts of chemical research · 2024
    Article
  19. Ferredoxin reduction by hydrogen with iron functions as an evolutionary precursor of flavin-based electron bifurcation.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

Max Brabender *Institute of Molecular Evolution, Faculty of Mathematics and Natural Sciences, Heinrich Heine University Düsseldorf, Düsseldorf 40225, Germany.ORCID 0009-0009-4983-5387
Delfina P Henriques Pereira *Microcosm Earth Center, Research Group for Geochemical Protozymes, Max Planck Institute for Terrestrial Microbiology and Philipps University, Marburg 35032, Germany.ORCID 0000-0001-6131-1740
Natalia Mrnjavac *Institute of Molecular Evolution, Faculty of Mathematics and Natural Sciences, Heinrich Heine University Düsseldorf, Düsseldorf 40225, Germany.ORCID 0009-0009-2849-6304
Manon Laura SchlikkerInstitute of Molecular Evolution, Faculty of Mathematics and Natural Sciences, Heinrich Heine University Düsseldorf, Düsseldorf 40225, Germany.ORCID 0009-0007-8175-5155
Zen-Ichiro KimuraInstitute of Molecular Evolution, Faculty of Mathematics and Natural Sciences, Heinrich Heine University Düsseldorf, Düsseldorf 40225, Germany.ORCID 0000-0003-3188-2213
Jeerus SucharitakulDepartment of Biochemistry, Chulalongkorn University, Patumwan, Bangkok 10330, Thailand.ORCID 0000-0002-3834-7961
Karl KleinermannsInstitute for Physical Chemistry, Faculty of Mathematics and Natural Sciences, Heinrich Heine University Düsseldorf, Düsseldorf 40225, Germany.
Harun TüysüzMax Planck Institute for Coal Research, Department of Heterogeneous Catalysis, Mülheim an der Ruhr 45470, Germany.ORCID 0000-0001-8552-7028
Wolfgang BuckelMax Planck Institute for Terrestrial Microbiology, Marburg 35043, Germany.ORCID 0000-0002-8280-1260
Martina PreinerMicrocosm Earth Center, Research Group for Geochemical Protozymes, Max Planck Institute for Terrestrial Microbiology and Philipps University, Marburg 35032, Germany.ORCID 0000-0001-5137-5556
William F MartinInstitute of Molecular Evolution, Faculty of Mathematics and Natural Sciences, Heinrich Heine University Düsseldorf, Düsseldorf 40225, Germany.ORCID 0000-0003-1478-6449
Heinrich Heine University Düsseldorf · DEMax Planck Institute for Terrestrial Microbiology · DEChulalongkorn University · THMax-Planck-Institut für Kohlenforschung · DENational Institute of Technology, Kure College · JPPhilipps University of Marburg · DE

Funding

European Research Council 101018894
6 · The paper itself

Abstract

Autotrophic theories for the origin of metabolism posit that the first cells satisfied their carbon needs from CO

Indexed as

FerredoxinsIronAcetyl Coenzyme ACarbon DioxideElectronsFlavinsHydrogenOxidation-ReductionAcetyl Coenzyme ACarbon DioxideFerredoxinsFlavinsHydrogenIronacetyl CoA pathwayorigin of lifeorigin of metabolismserpentinizationtransition metals

Identifiers

PMID38513105
PMCPMC7615787
OpenAlexW4393032809

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.