Evidence map›Paper›PMID 38513096›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

The disordered C-terminal tail of fungal LPMOs from phytopathogens mediates protein dimerization and impacts plant penetration.

Ketty C Tamburrini, Sayo Kodama, Sacha Grisel, Mireille Haon, Takumi Nishiuchi, Bastien Bissaro, Yasuyuki Kubo, Sonia Longhi, Jean-Guy Berrin

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Ketty C TamburriniCNRS Aix Marseille Université, CNRS, Architecture et Fonction des Macromolécules Biologiques, UMR 7257, Marseille 13009, France.ORCID 0000-0001-7803-1366
Sayo KodamaFaculty of Agriculture, Setsunan University, Osaka 573-0101, Japan.ORCID 0000-0003-0370-4882
Sacha GriselInstitut National de la Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Biodiversité et Biotechnologie Fongiques, UMR 1163, Aix Marseille Université, Marseille 13009, France.ORCID 0000-0001-6983-0107
Mireille HaonInstitut National de la Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Biodiversité et Biotechnologie Fongiques, UMR 1163, Aix Marseille Université, Marseille 13009, France.
Takumi NishiuchiDivision of Functional Genomics, Advanced Science Research Center, Kanazawa University, Kanazawa 920-1164, Japan.
Bastien BissaroInstitut National de la Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Biodiversité et Biotechnologie Fongiques, UMR 1163, Aix Marseille Université, Marseille 13009, France.ORCID 0000-0001-8354-3892
Yasuyuki KuboFaculty of Agriculture, Setsunan University, Osaka 573-0101, Japan.ORCID 0000-0002-8600-9705
Sonia LonghiCNRS Aix Marseille Université, CNRS, Architecture et Fonction des Macromolécules Biologiques, UMR 7257, Marseille 13009, France.ORCID 0000-0002-6829-6771
Jean-Guy BerrinInstitut National de la Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Biodiversité et Biotechnologie Fongiques, UMR 1163, Aix Marseille Université, Marseille 13009, France.ORCID 0000-0001-7570-3745
Aix-Marseille Université · FRCentre National de la Recherche Scientifique · FRSetsunan University · JPKanazawa University · JP

Funding

Agence Nationale de la Recherche (ANR) AMX-19-IET-006Agence Nationale de la Recherche (ANR) ANR-10-INSB- 0005MEXT | Japan Society for the Promotion of Science (JSPS) 20H02989MEXT | Japan Society for the Promotion of Science (JSPS) 20K15529MEXT | Japan Society for the Promotion of Science (JSPS) 23K13956Novo Nordisk Foundation Center for Basic Metabolic Research (NovoNordisk Foundation Center for Basic Metabolic Research) NNF20OC0059697
6 · The paper itself

Abstract

Lytic polysaccharide monooxygenases (LPMOs) are monocopper enzymes that oxidatively degrade various polysaccharides, such as cellulose. Despite extensive research on this class of enzymes, the role played by their C-terminal regions predicted to be intrinsically disordered (dCTR) has been overlooked. Here, we investigated the function of the dCTR of an LPMO, called

Indexed as

Fungal ProteinsPolysaccharidesCelluloseProtein MultimerizationScattering, Small AngleX-Ray DiffractionCelluloseFungal ProteinsPolysaccharidescellulosefungal pathogenintrinsically disordered regionoxidative enzymeplant cell wall

Identifiers

PMID38513096
PMCPMC10990093
OpenAlexW4393032781

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.