Evidence map›Paper›PMID 38512618›Full record

ArticleLa Radiologia medica2024

Locoregional staging of breast cancer: contrast-enhanced mammography versus breast magnetic resonance imaging.

Andrea Terzoni, Paola Basile, Anna Clelia Gambaro, Silvia Attanasio, Anna Maria Rampi, Marco Brambilla, Alessandro Carriero

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in La Radiologia medica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Andrea TerzoniScuola di Specializzazione Radiodiagnostica, University of Piemonte Orientale, Novara, Italy. dottortterzoni@gmail.com.ORCID http://orcid.org/0009-0009-0405-5176
Paola BasileScuola di Specializzazione Radiodiagnostica, University of Piemonte Orientale, Novara, Italy.
Anna Clelia GambaroSCDU Radiodiagnostica Maggiore della Carità, Novara, Italy.
Silvia AttanasioSCDU Radiodiagnostica Maggiore della Carità, Novara, Italy.
Anna Maria RampiSCDU Radiodiagnostica Maggiore della Carità, Novara, Italy.
Marco BrambillaHealth Physics Department, University Hospital, Novara, Italy.
Alessandro CarrieroSCDU Radiodiagnostica Maggiore della Carità, Novara, Italy.
Università degli Studi del Piemonte Orientale “Amedeo Avogadro” · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeBreast cancer diagnosis often involves assessing the locoregional spread of the disease through MRI, as multicentricity, multifocality and/or bilaterality are increasingly common. Contrast-enhanced mammography (CEM) is emerging as a potential alternative method. This study compares the performance of CEM and MRI in preoperative staging of women with confirmed breast carcinoma. Patients were also asked to fill in a satisfaction questionnaire to rate their comfort level with each investigation.

methodsFrom May 1st, 2021 to May 1st, 2022, we enrolled 70 women with confirmed breast carcinoma who were candidates for surgery. For pre-operative locoregional staging, all patients underwent CEM and MRI examination, which two radiologists evaluated blindly. We further investigated all suspicious locations for disease spread, identified by both CEM and MRI, with a second-look ultrasound (US) and eventual histological examination.

resultsIn our study cohort, MRI and CEM identified 114 and 102 areas of focal contrast enhancement, respectively. A true discrepancy between MRI and CEM occurred in 9 out of 70 patients examined. MRI reported 8 additional lesions that proved to be false positives on second-look US in 6 patients, while it identified 4 lesions that were not detected by CEM and were pathological (true positives) in 3 patients.

conclusionsCEM showed results comparable to MRI in the staging of breast cancer in our study population, with a high rate of patient acceptability.

Indexed as

Breast NeoplasmsBreastContrast MediaFemaleHumansMagnetic Resonance ImagingMammographyContrast MediaBreast cancerContrast-enhanced mammographyMagnetic resonance imaging

Identifiers

PMID38512618
PMCPMC11021306
OpenAlexW4393041285

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.