Evidence map›Paper›PMID 38512600›Full record

ReviewCurrent pain and headache reports2024

Literature Review: Mechanism, Indications, and Clinical Efficacy of Peripheral Nerve Stimulators in Lower Extremity Pain.

Qing Zhao Ruan, Jason Chang, Daniel Pak, Rajesh Supra, Cyrus Yazdi, Linda Kollenburg, Erkan Kurt, David Reece, Alexandra C G Fonseca, Alaa Abd-Elsayed and 1 more

Open access · greenAbstract readReview
PubMed Publisher
In one paragraph

Review in Current pain and headache reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 2 countries.

Qing Zhao RuanDepartment of Anesthesiology, Weill Cornell Medicine, 1300 York Ave, New York City, NY, 10021, USA. qzruan@gmail.com.
Jason ChangDepartment of Anesthesiology, Weill Cornell Medicine, 1300 York Ave, New York City, NY, 10021, USA.
Daniel PakDepartment of Anesthesiology, Weill Cornell Medicine, 1300 York Ave, New York City, NY, 10021, USA.
Rajesh SupraGeorgetown University School of Medicine, Washington, DC, USA.
Cyrus YazdiDepartment of Anesthesiology, Critical Care, and Pain Medicine, Harvard Medical School-Beth Israel Deaconess Medical Center, Boston, MA, USA.
Linda KollenburgDepartment of Neurosurgery, Radboud University Medical Center, Nijmegen, The Netherlands.
Erkan KurtDepartment of Neurosurgery, Radboud University Medical Center, Nijmegen, The Netherlands.
David ReeceAbsolute Pain Management, Rockville, MD, USA.
Alexandra C G FonsecaHarvard Medical School, Brigham and Women's Hospital, Department of Anesthesiology, Perioperative, and Pain Medicine, Boston, MA, USA.
Alaa Abd-ElsayedChronic Pain Medicine, Department of Anesthesiology, University of Wisconsin-Madison, Madison, USA.
Christopher L RobinsonDepartment of Anesthesiology, Critical Care, and Pain Medicine, Harvard Medical School-Beth Israel Deaconess Medical Center, Boston, MA, USA.
Weill Cornell Medicine · USHarvard University · USBeth Israel Deaconess Medical Center · USGeorgetown University · USPain Management Institute · USRadboud University Medical Center · NLRadboud University Nijmegen · NLUniversity of Wisconsin–Madison · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewLower extremity pain is deemed by Center for Disease Control and Prevention (CDC) to be a significant source of chronic pain in adults. If not appropriately managed, patients are subjected to risks of prolonged musculoskeletal dysfunction, disruption to quality of life, and elevated healthcare expenditures. Peripheral nerve stimulation (PNS) has shown great potential in recent years demonstrating efficacy in multiple diagnoses ranging from acute post-surgical pain to complex regional pain syndrome (CRPS). This study seeks to delineate efficacy of peripheral neuromodulation in the context of chronic lower extremity pain. RECENT

findingsPrevailing clinical studies demonstrate evidence levels ranging from II to V (Oxford Centre of Level of Evidence) in lower limb PNS, attaining positive outcomes in pain scores, opioid use, and quality of life measures. Nerves most frequently targeted are the sciatic and femoral nerves with post-amputation pain and CRPS most commonly investigated for efficacy. PNS is a promising therapeutic modality demonstrated to be effective for a variety of nociceptive and neuropathic pain conditions in the lower extremity. PNS offers chronic pain physicians a powerful tool in the multi-modal management of lower limb chronic pain.

Indexed as

Electric Stimulation TherapyLower ExtremityChronic PainHumansNeuralgiaPain ManagementPeripheral NervesTreatment OutcomeLeg painLower extremity painNeuropathic painPeripheral nerve stimulation

Identifiers

PMID38512600
OpenAlexW4393044954

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.