Evidence map›Paper›PMID 38512368›Full record

ArticleJournal of nephrology2024

The predictive value of systemic inflammatory markers in 902 patients with tunneled hemodialysis catheter.

Melis Baykara Ulusan, Emine Meltem, Ilhan Nahit Mutlu, Kivilcim Ulusan

Open access · hybridAbstract read
In one paragraph

Article in Journal of nephrology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Melis Baykara UlusanDepartment of Diagnostic and Interventional Radiology, Istanbul Training and Research Hospital, Samatya, Istanbul, Turkey. melisbulusan@gmail.com.ORCID 0000-0002-4728-1802
Emine MeltemDepartment of Diagnostic and Interventional Radiology, Istanbul Training and Research Hospital, Samatya, Istanbul, Turkey.
Ilhan Nahit MutluDepartment of Radiology, Department of Diagnostic and Interventional Radiology, Basaksehir Cam and Sakura City Hospital, Basaksehir, Istanbul, Turkey.
Kivilcim UlusanDepartment of General Surgery, Department of Endocrine Surgery, Istanbul Training and Research Hospital, Samatya, Istanbul, Turkey.
Eskişehir City Hospital · TRNpistanbul Brain Hospital · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThis study aimed to assess the predictive role of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, lymphocyte-to-monocyte ratio, and mean platelet volume, on catheter survival in chronic hemodialysis patients, analyzing both infectious and non-infectious complications.

methodsA retrospective analysis encompassed 1279 tunneled catheter insertion procedures involving 902 patients between March 2014 and October 2018. Patients were categorized into two main groups: (i) initial placement and (ii) exchange. The exchange group was further stratified into four subgroups: infection, dysfunction, displacement, and transitioning temporary hemodialysis catheters to long-term ones. Hematologic ratios were calculated from baseline hemogram data, including neutrophil, lymphocyte, monocyte, and platelet counts, while mean platelet volume was derived from the same hemogram.

resultsThe patients in the exchange group displayed significantly higher lymphocyte and monocyte values (p < 0.001), while lower values were noted for neutrophil-lymphocyte ratio and platelet-lymphocyte ratio (p < 0.001). The transition group displayed higher monocyte values and lower mean platelet volume and lymphocyte-monocyte ratio values (p < 0.05). In the infection-related exchange subgroup, higher neutrophil count, mean platelet volume, neutrophil-lymphocyte ratio, and platelet-lymphocyte ratio values were observed compared to other groups (p < 0.05). Cases related to catheter dysfunction exhibited increased lymphocyte-monocyte ratio but lower neutrophil, monocyte, neutrophil-lymphocyte ratio, and platelet-lymphocyte ratio values (p < 0.05).

conclusionThis study highlights the interest of specific inflammatory markers, particularly monocytes, neutrophil-lymphocyte ratio, and platelet-lymphocyte ratio, in the management of tunneled catheters, notably in patients undergoing exchanges. However, cut-off values, essential for constructing management algorithms, are currently lacking, and prospective multicenter studies are needed for further elucidation.

Indexed as

MonocytesNeutrophilsPredictive Value of TestsRenal DialysisAdultAgedBiomarkersBlood PlateletsCatheterization, Central VenousCatheter-Related InfectionsCatheters, IndwellingCentral Venous CathetersFemaleHumansInflammationLeukocyte CountBiomarkersHemodialysisLymphocyte-monocyte ratioMean platelet volumeNeutrophil–lymphocyte ratioPlatelet-lymphocyte ratioTunneled hemodialysis catheter

Identifiers

PMID38512368
PMCPMC11239775
OpenAlexW4393040736

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.