Evidence map›Paper›PMID 38512023›Full record

ArticleRadiology. Cardiothoracic imaging2024

Association of Impaired Left Ventricular Mitral Filling from 4D Flow Cardiac MRI and Prognosis of Hypertrophic Cardiomyopathy.

Hichem Sakhi, Gilles Soulat, Damian Craiem, Umit Gencer, Jérôme Lamy, Valentina Stipechi, Tania Puscas, Jean-Sébastien Hulot, Albert Hagege, Elie Mousseaux

Registry-linked trialOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Radiology. Cardiothoracic imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01091480 (French Hypertrophic Cardiomyopathy Observatory), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01091480 recruitingnot on this map

French Hypertrophic Cardiomyopathy Observatory

TypeobservationalSponsorFrench Cardiology SocietyRan2010 to 2028Enrolled600ConditionsHypertrophic Cardiomyopathy
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Impact of catheter ablation on atrial fibrillation outcomes in various cardiomyopathies: findings from LGE-MRI quantified atrial fibrosis analysis.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025
    Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Hichem SakhiFrom the Department of Radiology, AP-HP, Hôpital Européen Georges-Pompidou, 20-40 rue Leblanc, 75015 Paris, France (H.S., G.S., U.G., J.L., T.P., J.S.H., A.H., E.M.); Institut National de la Santé et de la Recherche Médicale, PARCC, Paris, France (G.S., U.G., J.L., J.S.H., A.H., E.M.); Université de Paris-Cité, Paris, France (G.S., J.S.H., A.H., E.M.); and Instituto de Medicina Traslacional, Trasplante y Bioingeniería (IMeTTyB), Universidad Favaloro-CONICET, Buenos Aires, Argentina (D.C., V.S.).ORCID 0009-0003-2225-9267
Gilles SoulatFrom the Department of Radiology, AP-HP, Hôpital Européen Georges-Pompidou, 20-40 rue Leblanc, 75015 Paris, France (H.S., G.S., U.G., J.L., T.P., J.S.H., A.H., E.M.); Institut National de la Santé et de la Recherche Médicale, PARCC, Paris, France (G.S., U.G., J.L., J.S.H., A.H., E.M.); Université de Paris-Cité, Paris, France (G.S., J.S.H., A.H., E.M.); and Instituto de Medicina Traslacional, Trasplante y Bioingeniería (IMeTTyB), Universidad Favaloro-CONICET, Buenos Aires, Argentina (D.C., V.S.).ORCID 0000-0003-4165-6113
Damian CraiemFrom the Department of Radiology, AP-HP, Hôpital Européen Georges-Pompidou, 20-40 rue Leblanc, 75015 Paris, France (H.S., G.S., U.G., J.L., T.P., J.S.H., A.H., E.M.); Institut National de la Santé et de la Recherche Médicale, PARCC, Paris, France (G.S., U.G., J.L., J.S.H., A.H., E.M.); Université de Paris-Cité, Paris, France (G.S., J.S.H., A.H., E.M.); and Instituto de Medicina Traslacional, Trasplante y Bioingeniería (IMeTTyB), Universidad Favaloro-CONICET, Buenos Aires, Argentina (D.C., V.S.).ORCID 0000-0003-1065-799X
Umit GencerFrom the Department of Radiology, AP-HP, Hôpital Européen Georges-Pompidou, 20-40 rue Leblanc, 75015 Paris, France (H.S., G.S., U.G., J.L., T.P., J.S.H., A.H., E.M.); Institut National de la Santé et de la Recherche Médicale, PARCC, Paris, France (G.S., U.G., J.L., J.S.H., A.H., E.M.); Université de Paris-Cité, Paris, France (G.S., J.S.H., A.H., E.M.); and Instituto de Medicina Traslacional, Trasplante y Bioingeniería (IMeTTyB), Universidad Favaloro-CONICET, Buenos Aires, Argentina (D.C., V.S.).ORCID 0000-0001-5329-7985
Jérôme LamyFrom the Department of Radiology, AP-HP, Hôpital Européen Georges-Pompidou, 20-40 rue Leblanc, 75015 Paris, France (H.S., G.S., U.G., J.L., T.P., J.S.H., A.H., E.M.); Institut National de la Santé et de la Recherche Médicale, PARCC, Paris, France (G.S., U.G., J.L., J.S.H., A.H., E.M.); Université de Paris-Cité, Paris, France (G.S., J.S.H., A.H., E.M.); and Instituto de Medicina Traslacional, Trasplante y Bioingeniería (IMeTTyB), Universidad Favaloro-CONICET, Buenos Aires, Argentina (D.C., V.S.).ORCID 0000-0003-1931-2971
Valentina StipechiFrom the Department of Radiology, AP-HP, Hôpital Européen Georges-Pompidou, 20-40 rue Leblanc, 75015 Paris, France (H.S., G.S., U.G., J.L., T.P., J.S.H., A.H., E.M.); Institut National de la Santé et de la Recherche Médicale, PARCC, Paris, France (G.S., U.G., J.L., J.S.H., A.H., E.M.); Université de Paris-Cité, Paris, France (G.S., J.S.H., A.H., E.M.); and Instituto de Medicina Traslacional, Trasplante y Bioingeniería (IMeTTyB), Universidad Favaloro-CONICET, Buenos Aires, Argentina (D.C., V.S.).
Tania PuscasFrom the Department of Radiology, AP-HP, Hôpital Européen Georges-Pompidou, 20-40 rue Leblanc, 75015 Paris, France (H.S., G.S., U.G., J.L., T.P., J.S.H., A.H., E.M.); Institut National de la Santé et de la Recherche Médicale, PARCC, Paris, France (G.S., U.G., J.L., J.S.H., A.H., E.M.); Université de Paris-Cité, Paris, France (G.S., J.S.H., A.H., E.M.); and Instituto de Medicina Traslacional, Trasplante y Bioingeniería (IMeTTyB), Universidad Favaloro-CONICET, Buenos Aires, Argentina (D.C., V.S.).
Jean-Sébastien HulotFrom the Department of Radiology, AP-HP, Hôpital Européen Georges-Pompidou, 20-40 rue Leblanc, 75015 Paris, France (H.S., G.S., U.G., J.L., T.P., J.S.H., A.H., E.M.); Institut National de la Santé et de la Recherche Médicale, PARCC, Paris, France (G.S., U.G., J.L., J.S.H., A.H., E.M.); Université de Paris-Cité, Paris, France (G.S., J.S.H., A.H., E.M.); and Instituto de Medicina Traslacional, Trasplante y Bioingeniería (IMeTTyB), Universidad Favaloro-CONICET, Buenos Aires, Argentina (D.C., V.S.).ORCID 0000-0001-5463-6117
Albert HagegeFrom the Department of Radiology, AP-HP, Hôpital Européen Georges-Pompidou, 20-40 rue Leblanc, 75015 Paris, France (H.S., G.S., U.G., J.L., T.P., J.S.H., A.H., E.M.); Institut National de la Santé et de la Recherche Médicale, PARCC, Paris, France (G.S., U.G., J.L., J.S.H., A.H., E.M.); Université de Paris-Cité, Paris, France (G.S., J.S.H., A.H., E.M.); and Instituto de Medicina Traslacional, Trasplante y Bioingeniería (IMeTTyB), Universidad Favaloro-CONICET, Buenos Aires, Argentina (D.C., V.S.).
Elie MousseauxFrom the Department of Radiology, AP-HP, Hôpital Européen Georges-Pompidou, 20-40 rue Leblanc, 75015 Paris, France (H.S., G.S., U.G., J.L., T.P., J.S.H., A.H., E.M.); Institut National de la Santé et de la Recherche Médicale, PARCC, Paris, France (G.S., U.G., J.L., J.S.H., A.H., E.M.); Université de Paris-Cité, Paris, France (G.S., J.S.H., A.H., E.M.); and Instituto de Medicina Traslacional, Trasplante y Bioingeniería (IMeTTyB), Universidad Favaloro-CONICET, Buenos Aires, Argentina (D.C., V.S.).ORCID 0000-0002-8076-1445
Université Paris Cité · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose To investigate whether the peak early filling rate normalized to the filling volume (PEFR/FV) estimated from four-dimensional (4D) flow cardiac MRI may be used to assess impaired left ventricular (LV) filling and predict clinical outcomes in individuals with hypertrophic cardiomyopathy (HCM). Materials and Methods Cardiac MRI with a 4D flow sequence and late gadolinium enhancement (LGE), as well as echocardiography, was performed in 88 individuals: 44 participants with HCM from a French prospective registry (ClinicalTrials.gov; NCT01091480) and 44 healthy volunteers matched for age and sex. In participants with HCM, a composite primary end point was assessed at follow-up, including unexplained syncope, new-onset atrial fibrillation, hospitalization for congestive heart failure, ischemic stroke, sustained ventricular arrhythmia, septal reduction therapy, and cardiac death. A Cox proportional hazard model was used to analyze associations with the primary end point. Results PEFR/FV was significantly lower in the HCM group (mean age, 51.8 years ± 18.5 [SD]; 29 male participants) compared with healthy volunteers (mean, 3.35 sec

Indexed as

Cardiomyopathy, HypertrophicContrast MediaGadoliniumHeart AtriaHumansMagnetic Resonance ImagingMaleMiddle AgedPrognosisContrast MediaGadolinium4D Flow SequenceCardiac MRIDiastolic FunctionHypertrophic CardiomyopathyLeft Ventricular Filling

Identifiers

PMID38512023
PMCPMC11058532
OpenAlexW4393062445

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.