Evidence map›Paper›PMID 38511206›Full record

ArticleACS infectious diseases2024

Impact of Methylthioxylose Substituents on the Biological Activities of Lipomannan and Lipoarabinomannan in

Zuzana Palčeková, Kavita De, Shiva Kumar Angala, Martine Gilleron, Sophie Zuberogoitia, Lucie Gouxette, Maritza Soto-Ojeda, Mercedes Gonzalez-Juarrero, Andrés Obregón-Henao, Jérôme Nigou and 2 more

Open access · greenAbstract read
In one paragraph

Article in ACS infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Exploiting thioether reactivity to label mycobacterial glycans.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Zuzana PalčekováMycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80523-1682, United States.
Kavita DeMycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80523-1682, United States.
Shiva Kumar AngalaMycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80523-1682, United States.
Martine GilleronInstitut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse 31077, France.
Sophie ZuberogoitiaInstitut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse 31077, France.
Lucie GouxetteInstitut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse 31077, France.
Maritza Soto-OjedaMycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80523-1682, United States.ORCID 0009-0008-0644-9104
Mercedes Gonzalez-JuarreroMycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80523-1682, United States.ORCID 0000-0002-4045-2365
Andrés Obregón-HenaoMycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80523-1682, United States.
Jérôme NigouInstitut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse 31077, France.
William H WheatMycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80523-1682, United States.
Mary JacksonMycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80523-1682, United States.ORCID 0000-0002-9212-0258
Colorado State University · USCentre National de la Recherche Scientifique · FR

Funding

Biogenesis of Lipoarabinomannan in MycobacteriaR01AI064798 · NIAID · COLORADO STATE UNIVERSITY-FORT COLLINS · PI JACKSON, MARY · 2005 to 2019
$5.4M
Tailoring modifications of polysaccharides in Mycobacterium tuberculosisR01AI167204 · NIAID · COLORADO STATE UNIVERSITY · PI GONZALEZ-JUARRERO, MERCEDES, JACKSON, MARY · 2021 to 2025
$3.1M
Assembly and export of mycobacterial lipoglycansR01AI155674 · NIAID · COLORADO STATE UNIVERSITY · PI JACKSON, MARY · 2021 to 2025
$3.0M
Tailoring modifications of polysaccharides in Mycobacterium tuberculosisR56AI145241 · NIAID · COLORADO STATE UNIVERSITY · PI GONZALEZ-JUARRERO, MERCEDES, JACKSON, MARY · 2020 to 2020
$667k
NIAID NIH HHS R01 AI064798NIAID NIH HHS R01 AI155674NIAID NIH HHS R01 AI167204NIAID NIH HHS R56 AI145241
6 · The paper itself

Abstract

Two lipoglycans, lipomannan (LM) and lipoarabinomannan (LAM), play various, albeit incompletely defined, roles in the interactions of mycobacteria with the host. Growing evidence points to the modification of LM and LAM with discrete covalent substituents as a strategy used by these bacteria to modulate their biological activities. One such substituent, originally identified in

Indexed as

Mycobacterium tuberculosisTuberculosisHumansLipopolysaccharideslipoarabinomannanlipomannanLipopolysaccharidesapoptosisinflammationlipoarabinomannanlipomannanmethylthioxyloseMycobacterium

Identifiers

PMID38511206
PMCPMC11014759
OpenAlexW4393054964

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.