Evidence map›Paper›PMID 38511090›Full record

ReviewAmerican heart journal plus : cardiology research and practice2023

Chronic rheumatologic disorders and cardiovascular disease risk in women.

Puja K Mehta, Rebecca D Levit, Malissa J Wood, Niti Aggarwal, Michelle L O'Donoghue, S Sam Lim, Kate Lindley, Scott Gaignard, Odayme Quesada, Nishant Vatsa and 5 more

Open access · goldAbstract readReview
In one paragraph

Review in American heart journal plus : cardiology research and practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Arrhythmias in Autoimmune Diseases: Immune-Mediated Mechanisms and Management.Journal of cardiovascular development and disease · 2026
    Review
  4. Inflammaging and Cardiovascular Risk in Old Women.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 9 institutions in 1 country.

Puja K MehtaEmory Women's Heart Center, Division of Cardiology, Emory University School of Medicine, Atlanta, GA, USA.
Rebecca D LevitEmory Women's Heart Center, Division of Cardiology, Emory University School of Medicine, Atlanta, GA, USA.
Malissa J WoodDivision of Cardiology, Massachusetts General Hospital, Boston, MA, USA.
Niti AggarwalDepartment of Cardiovascular Disease, Mayo Clinic, Rochester, MN, USA.
Michelle L O'DonoghueTIMI Study Group, Cardiovascular Division, Brigham and Women's Hospital, Boston, MA, USA.
S Sam LimDivision of Rheumatology, Department of Medicine, Emory University, Atlanta, GA, USA.
Kate LindleyCardiovascular Division, Washington University in St. Louis, USA.
Scott GaignardJ. Willis Hurst Internal Medicine Residency Program, Emory University, Atlanta, GA, USA.
Odayme QuesadaWomen's Heart Center, The Christ Hospital Heart and Vascular Institute, Cincinnati, OH, USA.
Nishant VatsaJ. Willis Hurst Internal Medicine Residency Program, Emory University, Atlanta, GA, USA.
Ana LeonEmory University School of Medicine, Atlanta, GA, USA.
Annabelle Santos VolgmanSection Division of Cardiology, Rush University Medical Center, Chicago, IL, USA.
Waddah MalasLoyola University Internal Medicine Residency Program, Chicago, IL, USA.
Carl J PepineDivision of Cardiovascular Medicine, University of Florida, Gainesville, FL, USA.
American College of Cardiology Cardiovascular Disease in Women Committee
Emory University · USChrist Hospital · USLoyola University Chicago · USMassachusetts General Hospital · USMayo Clinic in Arizona · USRush University Medical Center · USThrombolysis in Myocardial Infarction Study Group · USUniversity of Florida · USWashington University in St. Louis · US

Funding

Very early drivers of neutrophilic inflammation in cardiac ischemia-reperfusionR01HL140223 · NHLBI · EMORY UNIVERSITY · PI Rebecca Diane Levit · 2018 to 2026
$4.4M
Mental Stress Reactivity in Women with Coronary Microvascular DysfunctionR01HL157311 · NHLBI · EMORY UNIVERSITY · PI Puja Kiran Mehta · 2022 to 2026
$3.8M
Cardiac Autonomic Function in WomenK23HL105787 · NHLBI · EMORY UNIVERSITY · PI MEHTA, PUJA KIRAN · 2012 to 2016
$813k
NHLBI NIH HHS K23 HL105787NHLBI NIH HHS R01 HL140223NHLBI NIH HHS R01 HL157311
6 · The paper itself

Abstract

Cardiovascular disease (CVD) is a major health threat to women worldwide. In addition to traditional CVD risk factors, autoimmune conditions are increasingly being recognized as contributors to adverse CVD consequences in women. Chronic systemic autoimmune and inflammatory disorders can trigger premature and accelerated atherosclerosis, microvascular dysfunction, and thrombosis. The presence of comorbid conditions, duration of the autoimmune condition, disease severity, and treatment of underlying inflammation are all factors that impact CVD risk and progression. Early identification and screening of CVD risk factors in those with underlying autoimmune conditions may attenuate CVD in this population. Treatment with non-steroidal anti-inflammatory drugs, corticosteroids, disease modifying agents and biologics may influence CVD risk factors and overall risk. Multi-disciplinary and team-based care, clinical trials, and collaborative team-science studies focusing on systemic autoimmune conditions will be beneficial to advance care for women.

Indexed as

AutoimmuneInflammationWomen's heart disease

Identifiers

PMID38511090
PMCPMC10945906
OpenAlexW4319754520

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.