Evidence map›Paper›PMID 38510963›Full record

ReviewFrontiers in cellular and infection microbiology2024

A comprehensive review of monkeypox virus and mpox characteristics.

Emmanuel Alakunle, Daniel Kolawole, Diana Diaz-Cánova, Faith Alele, Oyelola Adegboye, Ugo Moens, Malachy Ifeanyi Okeke

Abstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

82 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. A review of bloodstream infections-pathogens, pathogenesis, diagnostic strategies, treatment methods-challenges and future aspects.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Mpox and the one health approach.Dialogues in health · 2026
    Review
  14. Article
  15. Therapeutic Innovations for Monkeypox Inhibition.International journal of molecular sciences · 2026
    Review
  16. Article
  17. Review
  18. An atypical case of infection with the Mpox virus clade IIb lineage C.1 - clinical and virological findings.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  19. Article
  20. Article

22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Emmanuel AlakunleDepartment of Natural and Environmental Sciences, American University of Nigeria, Yola, Nigeria.
Daniel KolawoleDepartment of Natural and Environmental Sciences, American University of Nigeria, Yola, Nigeria.
Diana Diaz-CánovaDepartment of Medical Biology, UIT - The Arctic University of Norway, Tromsø, Norway.
Faith AleleSchool of Health, University of the Sunshine Coast, Sippy Downs, QLD, Australia.
Oyelola AdegboyeMenzies School of Health Research, Charles Darwin University, Darwin, NT, Australia.
Ugo MoensDepartment of Medical Biology, UIT - The Arctic University of Norway, Tromsø, Norway.
Malachy Ifeanyi OkekeDepartment of Natural and Environmental Sciences, American University of Nigeria, Yola, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monkeypox virus (MPXV) is the etiological agent of monkeypox (mpox), a zoonotic disease. MPXV is endemic in the forested regions of West and Central Africa, but the virus has recently spread globally, causing outbreaks in multiple non-endemic countries. In this paper, we review the characteristics of the virus, including its ecology, genomics, infection biology, and evolution. We estimate by phylogenomic molecular clock that the B.1 lineage responsible for the 2022 mpox outbreaks has been in circulation since 2016. We interrogate the host-virus interactions that modulate the virus infection biology, signal transduction, pathogenesis, and host immune responses. We highlight the changing pathophysiology and epidemiology of MPXV and summarize recent advances in the prevention and treatment of mpox. In addition, this review identifies knowledge gaps with respect to the virus and the disease, suggests future research directions to address the knowledge gaps, and proposes a One Health approach as an effective strategy to prevent current and future epidemics of mpox.

Indexed as

Monkeypox virusMpox, MonkeypoxDisease OutbreaksEcologyGenomicsHumansantiviralsbiosafetyepidemiologyevolutiongenomicsinfection biologymonkeypoxone health

Identifiers

PMID38510963
PMCPMC10952103

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.