ArticleJournal of research in medical sciences : the official journal of Isfahan University of Medical Sciences2023
The effect of oral zinc on hemoglobin and dose of erythropoietin in hemodialysis patients.
Article in Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed, 0 citations in OpenAlex.
- Oyster-derived Zinc Exhibits Superior Anti-anemic Efficacy and Bioavailability Compared with Conventional Zinc Supplements.Biological trace element research · 2026Article
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7 authors at 2 institutions in 1 country.
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Abstract
Background: In hemodialysis (HD) patients, low serum zinc level could cause hyporesponsivity to erythropoiesis-stimulating agents and lead to anemia. This study investigated the effects of oral zinc supplements on the required dose of erythropoietin in patients undergoing HD. Materials and Methods: In a double-blinded randomized trial, 76 HD patients were assigned to 2 groups of 38. One group (intervention) was treated with oral zinc supplements of 210 mg, daily for 6 months, and the other group (control) used placebo capsules for 6 months. The serum zinc level, hemoglobin level, and required dose of erythropoietin, albumin, ferritin, ferrous, and total iron-binding capacity were evaluated 3 and 6 months after intervention. Results: Repeated measures ANOVA did not show a significant increase in Hb level after 6 months of intervention ( Conclusion: Oral zinc supplementation in HD patients could not increase hemoglobin level irrespective of their serum zinc level.
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