Evidence map›Paper›PMID 38510657›Full record

ArticleFrontiers in pharmacology2024

Epigenetic small-molecule screen for inhibition and reversal of acinar ductal metaplasia in mouse pancreatic organoids.

Kalina R Atanasova, Corey M Perkins, Ranjala Ratnayake, Jinmai Jiang, Qi-Yin Chen, Thomas D Schmittgen, Hendrik Luesch

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. The role of AMPK in pancreatic cancer: from carcinogenesis to treatment.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kalina R Atanasova *Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, FL, United States.
Corey M Perkins *Department of Pharmaceutics, College of Pharmacy, University of Florida, Gainesville, FL, United States.
Ranjala RatnayakeDepartment of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, FL, United States.
Jinmai JiangDepartment of Pharmaceutics, College of Pharmacy, University of Florida, Gainesville, FL, United States.
Qi-Yin ChenDepartment of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, FL, United States.
Thomas D SchmittgenDepartment of Pharmaceutics, College of Pharmacy, University of Florida, Gainesville, FL, United States.
Hendrik LueschDepartment of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, FL, United States.
University of Florida · US

Funding

Tissue Modeling & Drug Development Shared Resources CoreU54CA233444 · NCI · UNIVERSITY OF FLORIDA · PI JI-HYUN LEE · 2018 to 2026
$12.1M
Novel Targeted Anticancer Agents from Marine CyanobacteriaR01CA172310 · NCI · UNIVERSITY OF FLORIDA · PI HENDRIK LUESCH · 2013 to 2026
$5.8M
Development of Complex Natural Product Libraries and Multidimensional Anticancer Screening PlatformsR50CA211487 · NCI · UNIVERSITY OF FLORIDA · PI RATNAYAKE, RANJALA · 2016 to 2020
$440k
NCI NIH HHS R01 CA172310NCI NIH HHS R50 CA211487NCI NIH HHS U54 CA233444
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

acinar ductal metaplasiadrug screeningepigeneticslargazole and largazole homodimermarine natural productorganoidspancreatic cancer

Identifiers

PMID38510657
PMCPMC10953826
OpenAlexW4392518302

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.