Evidence map›Paper›PMID 38510557›Full record

ArticleTechnical innovations & patient support in radiation oncology2024

"Why am I still suffering?": Experience of long-term fatigue and neurocognitive changes in oropharyngeal cancer survivors following (chemo)radiotherapy.

Zsuzsanna Iyizoba-Ebozue, Emma Nicklin, James Price, Robin Prestwich, Sarah Brown, Emma Hall, John Lilley, Matthew Lowe, David J Thomson, Finbar Slevin and 2 more

Abstract read
In one paragraph

Article in Technical innovations & patient support in radiation oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Zsuzsanna Iyizoba-EbozueDepartment of Clinical Oncology, Leeds Cancer Centre, Leeds, UK.
Emma NicklinLeeds Institute of Medical Research, University of Leeds, Leeds, UK.
James PriceDepartment of Clinical Oncology, The Christie NHS Foundation Trust, Manchester, UK.
Robin PrestwichDepartment of Clinical Oncology, Leeds Cancer Centre, Leeds, UK.
Sarah BrownLeeds Cancer Research UK Clinical Trials Unit, Leeds Institute of Clinical Trials Research.
Emma HallThe Institute of Cancer Research, London, UK.
John LilleyDepartment of Radiotherapy Physics, Leeds Cancer Centre, Leeds, UK.
Matthew LoweChristie Medical Physics and Engineering, The Christie NHS Foundation Trust, Manchester, UK.
David J ThomsonDepartment of Clinical Oncology, The Christie NHS Foundation Trust, Manchester, UK.
Finbar SlevinDepartment of Clinical Oncology, Leeds Cancer Centre, Leeds, UK.
Louise MurrayDepartment of Clinical Oncology, Leeds Cancer Centre, Leeds, UK.
Florien BoeleLeeds Institute of Medical Research, University of Leeds, Leeds, UK.

Funding

Cancer Research UK 25447
6 · The paper itself

Abstract

Background: Late effects of cancer treatment, such as neurocognitive deficits and fatigue, can be debilitating. Other than head and neck-specific functional deficits such as impairments in swallowing and speech, little is known about survivorship after oropharyngeal cancer. This study examines the lived experience of fatigue and neurocognitive deficits in survivors of oropharyngeal squamous cell cancer and impact on their daily lives. Methods: This work is part of the multicentre mixed method ROC-oN study (Radiotherapy for Oropharyngeal Cancer and impact on Neurocognition), evaluating fatigue and neurocognitive function in patients following radiotherapy +/- chemotherapy for oropharyngeal cancer and impact on quality of life. Semi-structured interviews were conducted in adults treated with radiotherapy (+/-chemotherapy) for oropharyngeal squamous cell carcinoma >/=24 months from completing treatment. Reflexive thematic analysis performed. Results: 21 interviews (11 men and 10 women; median age 58 years and median time post-treatment 5 years) were conducted and analysed, yielding six themes: (1) Conclusions: Fatigue and neurocognitive impairment were frequently experienced by survivors of oropharyngeal cancer, at least two years after treatment. Patients felt ill-prepared for these late sequelae, highlighting opportunities for improvement of patient information and support services.

Indexed as

FatigueLate effectsNeurocognitionOropharyngeal CancerQuality of LifeRadiotherapy

Identifiers

PMID38510557
PMCPMC10951087

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.