Evidence map›Paper›PMID 38510498›Full record

ArticleAmerican heart journal plus : cardiology research and practice2023

Comparison of CT acquired cardiac valvular calcification scores in hemodialysis and peritoneal dialysis patients undergoing open heart surgery.

Christopher N Kanaan, Habib Layoun, Nicholas P Kondoleon, Remy Fadel, Saeid Mirzai, Jesse Schold, Susana Arrigain, Remy Daou, Ali Mehdi, Jonathan J Taliercio and 4 more

Open access · goldAbstract read
In one paragraph

Article in American heart journal plus : cardiology research and practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 2 countries.

Christopher N KanaanDepartment of Internal Medicine, Cleveland Clinic Foundation, Cleveland, OH, USA.
Habib LayounRobert and Suzanne Tomsich Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, OH, USA.
Nicholas P KondoleonDepartment of Internal Medicine, Cleveland Clinic Foundation, Cleveland, OH, USA.
Remy FadelDepartment of Internal Medicine, Cleveland Clinic Foundation, Cleveland, OH, USA.
Saeid MirzaiDepartment of Internal Medicine, Cleveland Clinic Foundation, Cleveland, OH, USA.
Jesse ScholdDepartment of Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, OH, USA.
Susana ArrigainDepartment of Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, OH, USA.
Remy DaouSaint Joseph University, Department of Family Medicine, Beirut, Lebanon.
Ali MehdiDepartment of Kidney Medicine, Glickman Urological and Kidney Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.
Jonathan J TaliercioDepartment of Kidney Medicine, Glickman Urological and Kidney Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.
Shinya UnaiDepartment of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, OH, USA.
Samir KapadiaRobert and Suzanne Tomsich Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, OH, USA.
Serge HarbRobert and Suzanne Tomsich Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, OH, USA.
Georges N NakhoulDepartment of Kidney Medicine, Glickman Urological and Kidney Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.
Cleveland Clinic · USSaint Joseph University · LB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Study objective: Data is scarce regarding which dialysis modality portends more severe cardiac valvular calcification (CVC). Our aim was to compare the degree of CVC in hemodialysis (HD) and peritoneal dialysis (PD) patient cohorts prior to open heart surgery (OHS) using a CT calcium score. Design setting and participants: Dialysis patients who underwent OHS at our institution from 2009 to 2019 and who had pre-surgical cardiac CT were included in our study. We obtained duration of dialysis modality prior to their surgical date. There were two study cohorts to evaluate outcomes of interest: mitral and aortic calcification. CVC was assessed using the Agatston score. Logistic regression was performed to test for the association of PD and HD cumulative dialysis duration with presence of CVC. Results: A total of 214 and 166 patients met inclusion for the mitral and aortic strata, respectively. Age, female sex, and BMI were associated with higher odds of presence of mitral calcification. Age and BMI were associated with higher odds of presence of aortic calcification, while female sex was associated with lower odds in the aortic strata. Cumulative years on PD and cumulative years on HD were not significantly associated with presence of CVC in either cohort. Conclusion: Presence of mitral and aortic calcification for patients undergoing OHS was not significantly associated with cumulative length of PD or HD after adjusting for age, gender, and BMI suggesting that there may be more factors at play in the progression of CVC in end stage renal disease patients than what was previously established.

Indexed as

Cardiac surgeryCardiac valvular calcificationCTHemodialysisPeritoneal dialysis

Identifiers

PMID38510498
PMCPMC10946039
OpenAlexW4310506987

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.