Linguistic markers for major depressive disorder: a cross-sectional study using an automated procedure.

Introduction: The identification of language markers, referring to both form and content, for common mental health disorders such as major depressive disorder (MDD), can facilitate the development of innovative tools for early recognition and prevention. However, studies in this direction are only at the beginning and are difficult to implement due to linguistic variability and the influence of cultural contexts. Aim: This study aims to identify language markers specific to MDD through an automated analysis process based on RO-2015 LIWC (Linguistic Inquiry and Word Count). Materials and methods: A sample of 62 medicated patients with MDD and a sample of 43 controls were assessed. Each participant provided language samples that described something that was pleasant for them. Assessment tools: (1) Screening tests for MDD (MADRS and DASS-21); (2) Ro-LIWC2015 - Linguistic Inquiry and Word Count - a computerized text analysis software, validated for Romanian Language, that analyzes morphology, syntax and semantics of word use. Results: Depressive patients use different approaches in sentence structure, and communicate in short sentences. This requires multiple use of the punctuation mark period, which implicitly requires directive communication, limited in exchange of ideas. Also, participants from the sample with depression mostly use impersonal pronouns, first person pronoun in plural form - not singular, a limited number of prepositions and an increased number of conjunctions, auxiliary verbs, negations, verbs in the past tense, and much less in the present tense, increased use of words expressing negative affects, anxiety, with limited use of words indicating positive affects. The favorite topics of interest of patients with depression are leisure, time and money. Conclusion: Depressive patients use a significantly different language pattern than people without mood or behavioral disorders, both in form and content. These differences are sometimes associated with years of education and sex, and might also be explained by cultural differences.