Evidence map›Paper›PMID 38509915›Full record

ArticleHeliyon2024

Co-detection of azoxystrobin and thiabendazole fungicides in mold and mildew resistant wallboards and in children.

Wenxin Hu, Yun-Chung Hsiao, Nikolas Morrison-Welch, Sophia Lamberti, Chih-Wei Liu, Weili Lin, Stephanie M Engel, Kun Lu, Mark J Zylka

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Identifying environmental chemicals impacting neurodevelopment using a random mixture-based screening approach.Toxicological sciences : an official journal of the Society of Toxicology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Wenxin HuUNC Neuroscience Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Yun-Chung HsiaoDepartment of Environmental Sciences and Engineering, The University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Nikolas Morrison-WelchUNC Neuroscience Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Sophia LambertiUNC Neuroscience Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Chih-Wei LiuDepartment of Environmental Sciences and Engineering, The University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Weili LinBiomedical Research Imaging Center and Department of Radiology, The University of North Carolina at Chapel Hill, North Carolina, USA.
Stephanie M EngelDepartment of Epidemiology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Kun LuDepartment of Environmental Sciences and Engineering, The University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Mark J ZylkaUNC Neuroscience Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
University of North Carolina at Chapel Hill · US

Funding

UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Melissa A. Troester · 2001 to 2026
$36.3M
Preclinical CoreP50HD103573 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Mark D Shen · 2020 to 2026
$9.7M
Environmental-use chemicals that target pathways linked to autism and other neurodevelopmental disordersR35ES028366 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Mark J. Zylka · 2019 to 2026
$6.8M
UNC/UMN Baby Connectome ProjectU01MH110274 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ELISON, JED THOMAS, GILMORE, JOHN HORACE · 2016 to 2019
$4.5M
Early Life Phthalate Exposures in Relation to Structural and Functional Brain DevelopmentR01ES033518 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Stephanie Engel, Weili Lin · 2021 to 2026
$3.3M
NICHD NIH HHS P50 HD103573NIEHS NIH HHS P30 ES010126NIEHS NIH HHS R01 ES033518NIEHS NIH HHS R35 ES028366NIMH NIH HHS U01 MH110274
6 · The paper itself

Abstract

The study measured the levels of azoxystrobin (AZ) and thiabendazole (TBZ) in wallboards and metabolite levels of these fungicides in children. The paper covering of wallboard samples contained a higher concentration of AZ and TBZ than the gypsum core, and similar amounts (w/w) of these two fungicides were present in the samples. These data suggest that commercial products containing a 1:1 (w/w) amount of AZ and TBZ, such as Sporgard® WB or Azo Tech™, were applied to the wallboard paper. This is the first detection of TBZ in mold-and-mildew resistant wallboards. The TBZ metabolite, 5OH-TBZ, was detected in 48% of urine samples collected from children aged 40-84 months, and was co-detected with AZ-acid, a common AZ metabolite, in 37.5% of the urine samples. The detection frequency of 5OH-TBZ was positively associated with the detection frequency of AZ-acid. These findings suggest that certain types of wallboards used in homes and commercial buildings may be a potential source of co-exposure to AZ and TBZ in humans.

Indexed as

AzoxystrobinExposure pathwayThiabendazoleWallboard

Identifiers

PMID38509915
PMCPMC10951607
OpenAlexW4392767773

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.