Evidence map›Paper›PMID 38509674›Full record

ReviewInfectious disorders drug targets2024

Imidazo[1,2-A]Pyridine: Potent Biological Activity, SAR and Docking Investigations (2017-2022).

Aditya Narayan, Shivkant Patel, Sunil B Baile, Surabhi Jain, Smriti Sharma

Abstract readReview
PubMed Publisher
In one paragraph

Review in Infectious disorders drug targets, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Imidazo[1,2‑ACS omega · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aditya NarayanCentre for Pharmaceutical Engineering Science, School of Pharmacy and Medical Sciences, University of Bradford, Richmond Road, Bradford BD7 1DP, United Kingdom.
Shivkant PatelDepartment of Pharmacy, Sumandeep Vidyapeeth Deemed to be University, At & Po. Piparia, Ta. Waghodia, 391760, Vadodara, Gujarat, India.
Sunil B BaileDepartment of Pharmacy, Sumandeep Vidyapeeth Deemed to be University, At & Po. Piparia, Ta. Waghodia, 391760, Vadodara, Gujarat, India.
Surabhi JainB. Pharmacy College Rampura-kakanpur, Gujarat Technological University, Panchmahals, Gujarat, India.
Smriti SharmaAmity Institute of Pharmacy, Amity University, Sector- 125, Noida, 201313, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRegarding scientific research, Imidazo[1,2-a] pyridine derivatives are constantly being developed due to the scaffold's intriguing chemical structure and varied biological activity. They are distinctive organic nitrogen-bridged heterocyclic compounds that have several uses in medicines, organometallics and natural products. It has become a vital tool for medicinal chemists.

methodsIn order to gather scientific information on Imidazo[1,2-a] pyridines derivative, Google, PubMed, Scopus, Google Scholar, and other databases were searched. In the current study, the medicinal value and therapeutic effect of Imidazo[1,2-a] pyridines were investigated using above mentioned databases. The current study analyzed the detailed pharmacological activities of Imidazo[1,2-a] pyridine analogs through literature from diverse scientific research works.

resultsDue to its wide range of biological activities, including antiulcer, anticonvulsant, antiprotozoal, anthelmintic, antiepileptic, antifungal, antibacterial, analgesic, antiviral, anticancer, anti-inflammatory, antituberculosis, and antitumor properties, imidazopyridine is one of the most significant structural skeletons in the field of natural and pharmaceutical products. An imidazopyridine scaffold serves as the basis for a number of therapeutically utilized medications, including zolpidem, alpidem, olprinone, zolimidine, and necopidem.

conclusionThis comprehensive study covers the period of the last five years, and it sheds light on the developments and emerging pharmacological actions of Imidazo[1,2-a] pyridines. Additionally, the structure-activity relationship and molecular docking studies are carefully documented throughout the paper, providing medicinal chemists with a clear picture for developing new drugs.

Indexed as

ImidazolesMolecular Docking SimulationPyridinesAnimalsAnti-Inflammatory AgentsAntineoplastic AgentsHumansStructure-Activity RelationshipAnti-Inflammatory AgentsAntineoplastic Agentsimidazo(1,2-a)pyridineImidazolesimidazopyridinePyridines2-a] pyridineanticanceranticonvulsantantimicrobialantiviral.biological sctivitiesimidazo[1Nitrogen-based heterocycleSAR analysissynthesis

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.