Evidence map›Paper›PMID 38509440›Full record

SynthesisCurrent osteoporosis reports2024

Diagnosing Osteoporosis in Diabetes-A Systematic Review on BMD and Fractures.

Inge Agnete Gerlach Brandt, Jakob Starup-Linde, Sally Søgaard Andersen, Rikke Viggers

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Current osteoporosis reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Risk factors for refracture or new vertebral compression fractures after percutaneous vertebroplasty: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Pooled it
  2. Prevalence, risk factors and adverse health outcomes of osteosarcopenia in middle-aged and older adults with type 2 diabetes mellitus-a scoping review.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Inge Agnete Gerlach BrandtSteno Diabetes Center North Denmark, Aalborg University Hospital, Aalborg, Denmark. i.gerlach@rn.dk.
Jakob Starup-LindeDepartment of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark.
Sally Søgaard AndersenSteno Diabetes Center North Denmark, Aalborg University Hospital, Aalborg, Denmark.
Rikke ViggersSteno Diabetes Center North Denmark, Aalborg University Hospital, Aalborg, Denmark.

Funding

Novo Nordisk Foundation, Denmark NNF18OC0052064Novo Nordisk Foundation, Denmark NNF20OC0065960
6 · The paper itself

Abstract

purpose of reviewRecently, the American Diabetes Association updated the 2024 guidelines for Standards of Care in Diabetes and recommend that a T-score of - 2.0 in patients with diabetes should be interpreted as equivalent to - 2.5 in people without diabetes. We aimed to evaluate the most recent findings concerning the bone mineral density (BMD)-derived T-score and risk of fractures related to osteoporosis in subjects with diabetes. RECENT

findingsThe dual-energy X-ray absorptiometry (DXA) scan is the golden standard for evaluating BMD. The BMD-derived T-score is central to fracture prediction and signifies both diagnosis and treatment for osteoporosis. However, the increased fracture risk in diabetes is not sufficiently explained by the T-score, complicating the identification and management of fracture risk in these patients. Recent findings agree that subjects with type 2 diabetes (T2D) have a higher T-score and higher fracture risk compared with subjects without diabetes. However, the actual number of studies evaluating the direct association of higher fracture risk at higher T-score levels is scant. Some studies support the adjustment based on the 0.5 BMD T-score difference between subjects with T2D and subjects without diabetes. However, further data from longitudinal studies is warranted to validate if the T-score treatment threshold necessitates modification to prevent fractures in subjects with diabetes.

Indexed as

Absorptiometry, PhotonBone DensityDiabetes Mellitus, Type 2OsteoporosisOsteoporotic FracturesHumansRisk FactorsDiabetes type 1Diabetes type 2DiagnosisFracturesMajor osteoporotic fractureOsteoporosis

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.