Evidence map›Paper›PMID 38509437›Full record

SynthesisCanadian journal of anaesthesia = Journal canadien d'anesthesie2024

Nonclinical factors affecting intraoperative red blood cell transfusion: a systematic review.

Tori Lenet, Pauline Berthelot, Alexa L Grudzinski, Alexander Banks, Joseph Tropiano, Daniel I McIsaac, Alan Tinmouth, Andrea M Patey, Dean A Fergusson, Guillaume Martel

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Improving blood transfusion practice: to give or to consider.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tori LenetDepartment of Surgery, The Ottawa Hospital, Ottawa, ON, Canada.
Pauline BerthelotFaculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
Alexa L GrudzinskiDepartment of Anesthesiology and Pain Medicine, University of Ottawa and The Ottawa Hospital, Ottawa, ON, Canada.
Alexander BanksDepartment of Surgery, The Ottawa Hospital, Ottawa, ON, Canada.
Joseph TropianoDepartment of Surgery, The Ottawa Hospital, Ottawa, ON, Canada.
Daniel I McIsaacDepartment of Anesthesiology and Pain Medicine, University of Ottawa and The Ottawa Hospital, Ottawa, ON, Canada.
Alan TinmouthDepartment of Medicine, The Ottawa Hospital, Ottawa, ON, Canada.
Andrea M PateyClinical Epidemiology Program, The Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Dean A FergussonClinical Epidemiology Program, The Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Guillaume MartelClinical Epidemiology Program, The Ottawa Hospital Research Institute, Ottawa, ON, Canada. gumartel@toh.ca.ORCID 0000-0002-1242-2601

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThere is significant variability in intraoperative red blood cell (RBC) transfusion practice. We aimed to use the theoretical domains framework (TDF) to categorize nonclinical and behavioural factors driving intraoperative RBC transfusion practice in a systematic review of the literature. SOURCE: We searched electronic databases from inception until August 2021 to identify studies evaluating nonclinical factors affecting intraoperative RBC transfusion. Using the Mixed Methods Appraisal Tool, we assessed the quality of included studies and identified relevant nonclinical factors, which were coded into TDF domains by two independent reviewers using NVivo (Lumivero, QSR International, Burlington, MA, USA). We identified common themes within domains and sorted domains based on the frequency of reported factors. PRINCIPAL

findingsOur systematic review identified 18 studies: nine retrospective cohort studies, six cross-sectional surveys, and three before-and-after studies. Factors related to the social influences, behavioural regulation, environmental context/resources, and beliefs about consequences domains of the TDF were the most reported factors. Key factors underlying the observed variability in transfusion practice included the social effects of peers, patients, and institutional culture on decision-making (social influences), and characteristics of the practice environment including case volume, geographic location, and case start time (environmental context/resources). Studies reported variable beliefs about the consequences of both intraoperative transfusion and anemia (beliefs about consequences). Provider- and institutional-level audits, educational sessions, and increased communication between surgeons/anesthesiologists were identified as strategies to optimize intraoperative transfusion decision-making (behavioural regulation).

conclusionOur systematic review has synthesized the literature on nonclinical and behavioural factors impacting intraoperative transfusion decision-making, categorized using the TDF. These findings can inform evidence-based interventions to reduce intraoperative RBC transfusion variability. STUDY REGISTRATION: Open Science Framework ( https://osf.io/pm8zs/?view_only=166299ed28964804b9360c429b1218c1 ; first posted, 3 August 2022).

Indexed as

Erythrocyte TransfusionIntraoperative CareHumansintraoperativered blood cell transfusiontheoretical domains frameworktransfusion behaviour

Identifiers

PMID38509437

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.