Evidence map›Paper›PMID 38509361›Full record

ArticleNature2024

Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site.

Takuro Shioi, Suguru Hatazawa, Eriko Oya, Noriko Hosoya, Wataru Kobayashi, Mitsuo Ogasawara, Takehiko Kobayashi, Yoshimasa Takizawa, Hitoshi Kurumizaka

Abstract read
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Article
  3. RAD51-targeting small molecule degrader sensitizesActa pharmaceutica Sinica. B · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
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  15. Article
  16. Review
  17. Article
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Takuro ShioiLaboratory of Chromatin Structure and Function, Institute for Quantitative Biosciences, The University of Tokyo, Tokyo, Japan.ORCID 0009-0005-8891-0037
Suguru HatazawaLaboratory of Chromatin Structure and Function, Institute for Quantitative Biosciences, The University of Tokyo, Tokyo, Japan.ORCID 0000-0002-5678-4049
Eriko OyaLaboratory of Genome Regeneration, Institute for Quantitative Biosciences, The University of Tokyo, Tokyo, Japan.
Noriko HosoyaLaboratory of Molecular Radiology, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.ORCID 0000-0002-1418-0677
Wataru KobayashiLaboratory of Chromatin Structure and Function, Institute for Quantitative Biosciences, The University of Tokyo, Tokyo, Japan.
Mitsuo OgasawaraLaboratory of Chromatin Structure and Function, Institute for Quantitative Biosciences, The University of Tokyo, Tokyo, Japan.
Takehiko KobayashiDepartment of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.
Yoshimasa TakizawaLaboratory of Chromatin Structure and Function, Institute for Quantitative Biosciences, The University of Tokyo, Tokyo, Japan.ORCID 0000-0002-6265-4830
Hitoshi KurumizakaLaboratory of Chromatin Structure and Function, Institute for Quantitative Biosciences, The University of Tokyo, Tokyo, Japan. kurumizaka@iqb.u-tokyo.ac.jp.ORCID 0000-0001-7412-3722

Funding

JSPS KAKENHIResearch Support Project for Life Science and Drug Discovery
6 · The paper itself

Abstract

RAD51 is the central eukaryotic recombinase required for meiotic recombination and mitotic repair of double-strand DNA breaks (DSBs)

Indexed as

Cryoelectron MicroscopyDNA Breaks, Double-StrandedNucleosomesRad51 RecombinaseSaccharomyces cerevisiae ProteinsDNADNA RepairHistonesHumansMutationProtein BindingProtein DomainsProtein SubunitsSaccharomyces cerevisiaeDNAHistonesNucleosomesProtein SubunitsRAD51 protein, humanRAD51 protein, S cerevisiaeRad51 RecombinaseSaccharomyces cerevisiae Proteins

Identifiers

PMID38509361
PMCPMC10990931

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.