Evidence map›Paper›PMID 38509356›Full record

ReviewPflugers Archiv : European journal of physiology2024

PHD1-3 oxygen sensors in vivo-lessons learned from gene deletions.

Agnieszka E Jucht, Carsten C Scholz

Abstract readReview
In one paragraph

Review in Pflugers Archiv : European journal of physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. How do cells sense oxygen?Pflugers Archiv : European journal of physiology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Agnieszka E JuchtInstitute of Physiology, University of Zurich, Zurich, 8057, Switzerland.ORCID 0000-0002-4553-4319
Carsten C ScholzInstitute of Physiology, University Medicine Greifswald, Friedrich-Ludwig-Jahn-Str. 15a, 17475, Greifswald, Germany. carsten.scholz@med.uni-greifswald.de.ORCID 0000-0001-6579-8015

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxygen sensors enable cells to adapt to limited oxygen availability (hypoxia), affecting various cellular and tissue responses. Prolyl-4-hydroxylase domain 1-3 (PHD1-3; also called Egln1-3, HIF-P4H 1-3, HIF-PH 1-3) proteins belong to the Fe

Indexed as

Hypoxia-Inducible Factor-Proline DioxygenasesAnimalsGene DeletionHumansHypoxiaHypoxia-Inducible Factor 1, alpha SubunitOxygenProcollagen-Proline DioxygenaseEGLN1 protein, humanEGLN2 protein, humanHypoxia-Inducible Factor 1, alpha SubunitHypoxia-Inducible Factor-Proline DioxygenasesOxygenProcollagen-Proline DioxygenaseEglnHIFHydroxylase inhibitorHypoxiaKnockoutMouse

Identifiers

PMID38509356
PMCPMC11310289

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.