Evidence map›Paper›PMID 38508231›Full record

ArticleDrug discovery today2024

Best practices for managing and disseminating resources and outreach and evaluating the impact of the IDG Consortium.

Dušica Vidović, Anna Waller, Jayme Holmes, Larry A Sklar, Stephan C Schürer

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Drug discovery today, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Dušica VidovićDepartment of Molecular and Cellular Pharmacology, Miller School of Medicine, University of Miami, Miami, FL, USA; Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL, USA.
Anna WallerDepartment of Pathology, Health Sciences Center, University of New Mexico, Albuquerque, NM, USA.
Jayme HolmesTranslational Informatics Division, Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, NM, USA.
Larry A SklarDepartment of Pathology, Health Sciences Center, University of New Mexico, Albuquerque, NM, USA; Autophagy, Inflammation, & Metabolism (AIM) Center, University of New Mexico, Albuquerque, NM, USA.
Stephan C SchürerDepartment of Molecular and Cellular Pharmacology, Miller School of Medicine, University of Miami, Miami, FL, USA; Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL, USA; Frost Institute for Data Science & Computing, University of Miami, Miami, FL, USA. Electronic address: sschurer@miami.edu.
University of New Mexico · USSylvester Comprehensive Cancer Center · US

Funding

Unfolded Protein Response and Autophagy in T Helper Cell Effector FunctionP20GM121176 · NIGMS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Samuel Joseph Endicott · 2017 to 2026
$24.9M
Resource Dissemination and Outreach Center for Illuminating the Druggable GenomeU24TR002278 · NCATS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI SCHURER, STEPHAN C, SKLAR, LARRY A. · 2018 to 2023
$3.7M
Unifying Templates, Ontologies and Tools to Achieve Effective Annotation of Bioassay ProtocolsU01LM012630 · NLM · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI BUNIN, BARRY A, MUSEN, MARK A · 2017 to 2020
$2.1M
Automated Molecular Identity Disambiguator (AutoMID)R01LM013391 · NLM · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI BUNIN, BARRY A, SCHURER, STEPHAN C · 2020 to 2023
$1.1M
NCATS NIH HHS U24 TR002278NIGMS NIH HHS P20 GM121176NLM NIH HHS R01 LM013391NLM NIH HHS U01 LM012630
6 · The paper itself

Abstract

The Illuminating the Druggable Genome (IDG) consortium generated reagents, biological model systems, data, informatic databases, and computational tools. The Resource Dissemination and Outreach Center (RDOC) played a central administrative role, organized internal meetings, fostered collaboration, and coordinated consortium-wide efforts. The RDOC developed and deployed a Resource Management System (RMS) to enable efficient workflows for collecting, accessing, validating, registering, and publishing resource metadata. IDG policies for repositories and standardized representations of resources were established, adopting the FAIR (findable, accessible, interoperable, reusable) principles. The RDOC also developed metrics of IDG impact. Outreach initiatives included digital content, the Protein Illumination Timeline (representing milestones in generating data and reagents), the Target Watch publication series, the e-IDG Symposium series, and leveraging social media platforms.

Indexed as

Information DisseminationDatabases, FactualHumansdruggable genomeFAIR datametadata managementoutreachresource disseminationunderstudied proteins

Identifiers

PMID38508231
PMCPMC11335350
OpenAlexW4392907256

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.