Evidence map›Paper›PMID 38508143›Full record

ArticleCell reports. Medicine2024

Activation of hepatic adenosine A1 receptor ameliorates MASH via inhibiting SREBPs maturation.

Weize Zhu, Ying Hong, Zhaowei Tong, Xiaofang He, Yan Li, Hao Wang, Xinxin Gao, Pengtao Song, Xianshan Zhang, Xiaochang Wu and 14 more

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell reports. Medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Liver diseases: epidemiology, causes, trends and predictions.Signal transduction and targeted therapy · 2025
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

24 authors at 6 institutions in 2 countries.

Weize ZhuSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Ying HongSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Zhaowei TongHuzhou Key Laboratory of Precision Medicine Research and Translation for Infectious Diseases, Huzhou Central Hospital, Affiliated Central Hospital Huzhou University, Huzhou 313000, China.
Xiaofang HeSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Yan LiSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Hao WangSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Xinxin GaoSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Pengtao SongDepartment of Pathology, Huzhou Central Hospital, Affiliated Central Hospital Huzhou University, Huzhou 313000, China.
Xianshan ZhangHuzhou Key Laboratory of Precision Medicine Research and Translation for Infectious Diseases, Huzhou Central Hospital, Affiliated Central Hospital Huzhou University, Huzhou 313000, China.
Xiaochang WuDepartment of Hepatobiliary Surgery, Huzhou Central Hospital, Affiliated Central Hospital Huzhou University, Huzhou 313000, China.
Zhenhua TanDepartment of Hepatobiliary Surgery, Huzhou Central Hospital, Affiliated Central Hospital Huzhou University, Huzhou 313000, China.
Wenjin HuangSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Zekun LiuSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Yiyang BaoSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Junli MaSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Ningning ZhengSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Cen XieShanghai Frontiers Science Center of TCM Chemical Biology, Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Xisong KeState Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Wen ZhouKey Laboratory of Veterinary Chemical Drugs and Pharmaceutics, Ministry of Agriculture and Rural, Affairs, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai 200241, China.
Wei JiaSchool of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong 999077, China.
Mingxiao LiSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. Electronic address: mingxiaoli0928@126.com.
Jing ZhongHuzhou Key Laboratory of Precision Medicine Research and Translation for Infectious Diseases, Huzhou Central Hospital, Affiliated Central Hospital Huzhou University, Huzhou 313000, China. Electronic address: Zhongjing1003@126.com.
Lili ShengSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. Electronic address: llsheng@shutcm.edu.cn.
Houkai LiSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. Electronic address: hk_li@shutcm.edu.cn.
Shanghai University of Traditional Chinese Medicine · CNHuzhou Central Hospital · CNHuzhou University · CNChinese Academy of Sciences · CNHong Kong Baptist University · HKMinistry of Agriculture and Rural Affairs · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolic (dysfunction)-associated steatohepatitis (MASH) is the advanced stage of metabolic (dysfunction)-associated fatty liver disease (MAFLD) lacking approved clinical drugs. Adenosine A1 receptor (A

Indexed as

Fatty LiverReceptor, Adenosine A1AnimalsDiet, High-FatHumansLipogenesisMiceReceptor, Adenosine A1adenosine A1 receptorde novo lipogenesisinflammationMASHSCAP-SREBPs pathway

Identifiers

PMID38508143
PMCPMC10983109
OpenAlexW4393060478

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.