SynthesisThe American journal of tropical medicine and hygiene2024
Snakebite-Associated Infections: A Systematic Review and Meta-Analysis.
Synthesis in The American journal of tropical medicine and hygiene, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- The role of antimicrobial prophylaxis in the management of snakebite: a systematic review.Wellcome open research · 2025Pooled it
- Trial
- Management of Naja kaouthia Envenomation at a Quaternary Urban Medical Center: A Case Report.Journal of orthopaedic case reports · 2026Article
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- Cobra bite complicated by soft tissue infection withIDCases · 2026Article
- Upper limb compartment syndrome requiring fasciotomies following aCase reports in plastic surgery & hand surgery · 2026Article
- Varespladib attenuatesRedox report : communications in free radical research · 2025Article
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- Maresin 2, a Specialized Pro-Resolution Lipid Mediator, Reduces Pain and Inflammation Induced byToxins · 2025Article
- Draft genome sequences of twoMicrobiology resource announcements · 2025Article
- Successful treatment of necrotising fasciitis following cobra bite: a case report.Journal of surgical case reports · 2025Article
- Detection and Whole-Genome Characteristics ofPathogens (Basel, Switzerland) · 2025Article
- Secondary infection with Aeromonas hydrophila and death of two patients with probable Bothrops envenomation.Revista da Sociedade Brasileira de Medicina Tropical · 2025Article
- Antibiotic Therapy and Prophylaxis for Snake-Bitten Patients.The American journal of tropical medicine and hygiene · 2024Article
- The Chinese guideline for management of snakebites.World journal of emergency medicine · 2024Article
Corrections and comments
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Authors and funding
11 authors at 7 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Snakebites still constitute a significant public health problem in developing countries and are considered a neglected tropical condition by the WHO. Snake accidents are associated with substantial morbidity and mortality and may produce secondary complications, such as severe infections. The objective of this systematic review was to determine the prevalence of snakebite infections and characterize the bacteria isolated from these infections. A systematic literature review in five databases was carried out to assess the prevalence of snakebite infection. A meta-analysis was performed using a random-effects model to calculate the pooled prevalence and 95% CIs. Cochran's Q test and the I2 statistic were used to assess between-study heterogeneity. The pooled prevalence of infection due to snakebite was 27.0% (95% CI: 22.0-32.0%), with high heterogeneity among studies (I2 = 99.7%). The prevalence was higher in Asia (32%) than in the Americas (21%). Snakebite infections required surgical interventions in 68% (95% CI: 37.0-98.0%). The leading group of pathogens identified corresponded to Gram-negative bacteria (63%), particularly Morganella morganii (32%), but also, Gram-positive cocci (40%), especially Enterococcus spp. (23%) and Staphylococcus aureus (15%). However, multiple other pathogens, including anaerobes, were found. A high prevalence of snakebite-associated infection has been described, primarily due to M. morganii, with the corresponding implications for empirical therapy. Rational use of antimicrobials is recommended, and this should guide initial empirical treatment. Moreover, isolation and identification of the possible bacteria present in snakebite wounds is recommended in all cases to confirm or rule out associated infection.
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