Evidence map›Paper›PMID 38507790›Full record

ArticleACS applied materials & interfaces2024

Co-immobilization of Ciprofloxacin and Chlorhexidine as a Broad-Spectrum Antimicrobial Dual-Drug Coating for Poly(vinyl chloride) (PVC)-Based Endotracheal Tubes.

Diana Filipa Alves, Maria Olívia Pereira, Susana Patrícia Lopes

Erratum issuedOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS applied materials & interfaces, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Diana Filipa AlvesCEB - Centre of Biological Engineering, University of Minho, 4710-057 Braga, Portugal.ORCID 0000-0001-8750-5439
Maria Olívia PereiraCEB - Centre of Biological Engineering, University of Minho, 4710-057 Braga, Portugal.ORCID 0000-0002-4307-3985
Susana Patrícia LopesCEB - Centre of Biological Engineering, University of Minho, 4710-057 Braga, Portugal.ORCID 0000-0002-8183-1695
University of Minho · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The endotracheal tube (ETT) affords support for intubated patients, but the increasing incidence of ventilator-associated pneumonia (VAP) is jeopardizing its application. ETT surfaces promote (poly)microbial colonization and biofilm formation, with a heavy burden for VAP. Devising safe, broad-spectrum antimicrobial materials to tackle the ETT bioburden is needful. Herein, we immobilized ciprofloxacin (CIP) and/or chlorhexidine (CHX), through polydopamine (pDA)-based functionalization, onto poly(vinyl chloride) (PVC) surfaces. These surfaces were characterized regarding physicochemical properties and challenged with single and polymicrobial cultures of VAP-relevant bacteria (

Indexed as

Anti-Infective AgentsPneumonia, Ventilator-AssociatedVinyl ChlorideBacteriaBiofilmsChlorhexidineCiprofloxacinHumansIntubation, IntratrachealPseudomonas aeruginosaStaphylococcus aureusAnti-Infective AgentsChlorhexidineCiprofloxacinVinyl Chlorideco-immobilizationdual-drug coatingendotracheal tubepolymicrobial biofilmventilator-associated pneumonia

Identifiers

PMID38507790
PMCPMC10995906
OpenAlexW4392975616

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.