Evidence map›Paper›PMID 38507610›Full record

ArticleAmerican journal of respiratory and critical care medicine2024

CRISPR-Cas9 Genome Editing Allows Generation of the Mouse Lung in a Rat.

Bingqiang Wen, Enhong Li, Guolun Wang, Timothy R Kalin, Dengfeng Gao, Peixin Lu, Tanya V Kalin, Vladimir V Kalinichenko

Open access · greenAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. The making of cells and organs in xenogeneic animal bioreactor.Signal transduction and targeted therapy · 2026
    Review
  2. Article
  3. Recent advances in interspecies chimeras and organogenesis.Current opinion in genetics & development · 2025
    Review
  4. Review
  5. Review
  6. Can a Rat Breathe through a Mouse's Lung?American journal of respiratory and critical care medicine · 2024
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Bingqiang WenPhoenix Children's Research Institute, Department of Child Health, College of Medicine Phoenix, University of Arizona, Phoenix, Arizona.
Enhong LiPhoenix Children's Research Institute, Department of Child Health, College of Medicine Phoenix, University of Arizona, Phoenix, Arizona.
Guolun WangDivision of Pulmonary Biology and.
Timothy R KalinCollege of Arts and Sciences, University of Cincinnati, Cincinnati, Ohio.
Dengfeng GaoState Key Laboratory of Animal Biotech Breeding, College of Biological Sciences, China Agricultural University, Beijing, China; and.
Peixin LuDivision of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Tanya V KalinPhoenix Children's Research Institute, Department of Child Health, College of Medicine Phoenix, University of Arizona, Phoenix, Arizona.
Vladimir V KalinichenkoPhoenix Children's Research Institute, Department of Child Health, College of Medicine Phoenix, University of Arizona, Phoenix, Arizona.
University of Arizona · USChina Agricultural University · CNCincinnati Children's Hospital Medical Center · USPhoenix Children's Hospital · USPulmonary Associates · US

Funding

Transcriptional Regulation of Endothelial Cells after Neonatal Lung InjuryR01HL141174 · NHLBI · UNIVERSITY OF ARIZONA · PI Vladimir Kalinichenko · 2018 to 2026
$4.7M
Development of novel therapeutic approaches for treatment of Alveolar Capillary DysplasiaR01HL152973 · NHLBI · UNIVERSITY OF ARIZONA · PI Vladimir Kalinichenko · 2021 to 2026
$3.6M
Molecular Mechanisms Regulated by FOXM1 in Chronic Lung RemodelingR01HL149631 · NHLBI · UNIVERSITY OF ARIZONA · PI KALINICHENKO, VLADIMIR · 2020 to 2022
$2.2M
Role of lung endothelial cells during fibrotic lung remodeling.R01HL158659 · NHLBI · UNIVERSITY OF ARIZONA · PI KALIN, TANYA · 2021 to 2024
$2.2M
Role of Foxm1 in Lung Cancer MicroenvironmentR01CA142724 · NCI · CINCINNATI CHILDRENS HOSP MED CTR · PI KALIN, TANYA · 2010 to 2014
$1.5M
Targeting Foxm1 in pulmonary fibrosisR01HL132849 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI KALIN, TANYA · 2016 to 2019
$1.5M
Theraputic targeting of pulmonary endothelial cells to inhibit pathological lung remodelingR01HL177800 · NHLBI · UNIVERSITY OF ARIZONA · PI Tanya Kalin · 2025 to 2026
$1.4M
NCI NIH HHS R01 CA142724NHLBI NIH HHS HL141174NHLBI NIH HHS HL149631NHLBI NIH HHS HL152973NHLBI NIH HHS LH132849NHLBI NIH HHS R01 HL132849NHLBI NIH HHS R01 HL141174NHLBI NIH HHS R01 HL149631NHLBI NIH HHS R01 HL152973NHLBI NIH HHS R01 HL158659NHLBI NIH HHS R01 HL177800
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CRISPR-Cas SystemsGene EditingLungAnimalsEmbryonic Stem CellsMiceRatsThyroid Nuclear Factor 1Thyroid Nuclear Factor 1blastocyst complementationCRISPR-Cas9embryonic stem cellsneonatal lung tissueNKX2-1

Identifiers

PMID38507610
PMCPMC11273307
OpenAlexW4392972985

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.