Evidence map›Paper›PMID 38507598›Full record

ArticleACS synthetic biology2024

Minimal Bacterial Cell JCVI-syn3B as a Chassis to Investigate Interactions between Bacteria and Mammalian Cells.

Daniela Matias de C Bittencourt, David M Brown, Nacyra Assad-Garcia, Michaela R Romero, Lijie Sun, Luis Alberto M Palhares de Melo, Marcelo Freire, John I Glass

Open access · hybridAbstract read
In one paragraph

Article in ACS synthetic biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Selection-free whole genome transplantation revives dead microbes.bioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Rapid assembly of functional modules for generating human artificial chromosome constructs compatible with epigenetic centromere seeding.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Daniela Matias de C BittencourtThe J. Craig Venter Institute, 4120 Capricorn Lane, La Jolla, California 92037, United States.
David M BrownThe J. Craig Venter Institute, 9605 Medical Center Drive, Suite 150, Rockville, Maryland 20850, United States.
Nacyra Assad-GarciaThe J. Craig Venter Institute, 9605 Medical Center Drive, Suite 150, Rockville, Maryland 20850, United States.
Michaela R RomeroThe J. Craig Venter Institute, 4120 Capricorn Lane, La Jolla, California 92037, United States.
Lijie SunThe J. Craig Venter Institute, 4120 Capricorn Lane, La Jolla, California 92037, United States.
Luis Alberto M Palhares de MeloEmbrapa Genetic Resources and Biotechnology/National Institute of Science and Technology - Synthetic Biology, Parque Estação Biológica, PqEB, Av. W5 Norte (final), Brasília, DF 70770-917, Brazil.
Marcelo FreireThe J. Craig Venter Institute, 4120 Capricorn Lane, La Jolla, California 92037, United States.
John I GlassThe J. Craig Venter Institute, 4120 Capricorn Lane, La Jolla, California 92037, United States.ORCID 0000-0002-3784-5301
J. Craig Venter Institute · USBrazilian Agricultural Research Corporation · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mycoplasmas are atypical bacteria with small genomes that necessitate colonization of their respective animal or plant hosts as obligate parasites, whether as pathogens, or commensals. Some can grow axenically in specialized complex media yet show only host-cell-dependent growth in cell culture, where they can survive chronically and often through interactions involving surface colonization or internalization. To develop a mycoplasma-based system to identify genes mediating such interactions, we exploited genetically tractable strains of the goat pathogen

Indexed as

MycoplasmaMycoplasma mycoidesAnimalsHeLa CellsHumansMammalsbacteria−mammalian cell interactionscell cultureimmunological responseminimal cellmycoplasmas

Identifiers

PMID38507598
PMCPMC11036491
OpenAlexW4392973000

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.