Evidence map›Paper›PMID 38507494›Full record

ArticleScience advances2024

Millimeter-scale magnetic implants paired with a fully integrated wearable device for wireless biophysical and biochemical sensing.

Ji Wan, Zhongyi Nie, Jie Xu, Zixuan Zhang, Shenglian Yao, Zehua Xiang, Xiang Lin, Yuxing Lu, Chen Xu, Pengcheng Zhao and 8 more

Abstract read
In one paragraph

Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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  16. Smart Dust for Chemical Mapping.Advanced materials (Deerfield Beach, Fla.) · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Ji WanNational Key Laboratory of Science and Technology on Micro/Nano Fabrication, Department of Biomedical Engineering, College of Future Technology, Peking University, Beijing, China.ORCID 0000-0002-6232-2908
Zhongyi NieNational Key Laboratory of Science and Technology on Micro/Nano Fabrication, Department of Biomedical Engineering, College of Future Technology, Peking University, Beijing, China.ORCID 0009-0008-0869-9588
Jie XuNational Key Laboratory of Science and Technology on Micro/Nano Fabrication, Department of Biomedical Engineering, College of Future Technology, Peking University, Beijing, China.
Zixuan ZhangSchool of Electronic and Computer Engineering, Peking University, Shenzhen, China.ORCID 0009-0005-4724-5667
Shenglian YaoSchool of Materials Science and Engineering, University of Science and Technology Beijing, Beijing, China.ORCID 0000-0001-7734-9399
Zehua XiangNational Key Laboratory of Science and Technology on Micro/Nano Fabrication, Department of Biomedical Engineering, College of Future Technology, Peking University, Beijing, China.
Xiang LinNational Key Laboratory of Science and Technology on Micro/Nano Fabrication, Department of Biomedical Engineering, College of Future Technology, Peking University, Beijing, China.ORCID 0009-0003-6616-5182
Yuxing LuDepartment of Bigdata and Biomedical AI, College of Future Technology, Peking University, Beijing, China.ORCID 0000-0002-8207-4411
Chen XuNational Key Laboratory of Science and Technology on Micro/Nano Fabrication, Department of Biomedical Engineering, College of Future Technology, Peking University, Beijing, China.
Pengcheng ZhaoNational Key Laboratory of Science and Technology on Micro/Nano Fabrication, Department of Biomedical Engineering, College of Future Technology, Peking University, Beijing, China.
Yiran WangNational Key Laboratory of Science and Technology on Micro/Nano Fabrication, Department of Biomedical Engineering, College of Future Technology, Peking University, Beijing, China.
Jingyan ZhangNational Key Laboratory of Science and Technology on Micro/Nano Fabrication, Department of Biomedical Engineering, College of Future Technology, Peking University, Beijing, China.
Yaozheng WangNational Key Laboratory of Science and Technology on Micro/Nano Fabrication, Department of Biomedical Engineering, College of Future Technology, Peking University, Beijing, China.
Shaotong ZhangYuanpei College, Peking University, Beijing, China.
Jinzhuo WangDepartment of Bigdata and Biomedical AI, College of Future Technology, Peking University, Beijing, China.ORCID 0000-0002-9464-4426
Weitao ManDepartment of Neurosurgery, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China.ORCID 0000-0003-4269-5392
Min ZhangSchool of Electronic and Computer Engineering, Peking University, Shenzhen, China.ORCID 0000-0002-2225-8024
Mengdi HanNational Key Laboratory of Science and Technology on Micro/Nano Fabrication, Department of Biomedical Engineering, College of Future Technology, Peking University, Beijing, China.ORCID 0000-0002-7552-7398

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Implantable sensors can directly interface with various organs for precise evaluation of health status. However, extracting signals from such sensors mainly requires transcutaneous wires, integrated circuit chips, or cumbersome readout equipment, which increases the risks of infection, reduces biocompatibility, or limits portability. Here, we develop a set of millimeter-scale, chip-less, and battery-less magnetic implants paired with a fully integrated wearable device for measuring biophysical and biochemical signals. The wearable device can induce a large amplitude damped vibration of the magnetic implants and capture their subsequent motions wirelessly. These motions reflect the biophysical conditions surrounding the implants and the concentration of a specific biochemical depending on the surface modification. Experiments in rat models demonstrate the capabilities of measuring cerebrospinal fluid (CSF) viscosity, intracranial pressure, and CSF glucose levels. This miniaturized system opens the possibility for continuous, wireless monitoring of a wide range of biophysical and biochemical conditions within the living organism.

Indexed as

Wearable Electronic DevicesWireless TechnologyAnimalsMagnetic PhenomenaPhysical PhenomenaProstheses and ImplantsRats

Identifiers

PMID38507494
PMCPMC10954204

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.