Evidence map›Paper›PMID 38507422›Full record

ArticlePloS one2024

Antihypertensive medication persistence and adherence among non-Hispanic Asian US patients with hypertension and fee-for-service Medicare health insurance.

Eunhee Choi, Hiroyuki Mizuno, Zhixin Wang, Chloe Fang, Matthew T Mefford, Kristi Reynolds, Lama Ghazi, Daichi Shimbo, Paul Muntner

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Gut Butyrate and Blood Pressure: Insights From Recent Clinical Trials.Journal of the American Heart Association · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Eunhee ChoiThe Columbia Hypertension Center and Lab, Columbia University Irving Medical Center, New York, New York, United Kingdom.ORCID 0000-0002-3449-0672
Hiroyuki MizunoThe Columbia Hypertension Center and Lab, Columbia University Irving Medical Center, New York, New York, United Kingdom.
Zhixin WangDepartment of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Chloe FangThe Columbia Hypertension Center and Lab, Columbia University Irving Medical Center, New York, New York, United Kingdom.
Matthew T MeffordDepartment of Research and Evaluation, Kaiser Permanente of Southern California, Pasadena, California, United States of America.
Kristi ReynoldsDepartment of Research and Evaluation, Kaiser Permanente of Southern California, Pasadena, California, United States of America.ORCID 0000-0001-7619-1649
Lama GhaziDepartment of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Daichi ShimboThe Columbia Hypertension Center and Lab, Columbia University Irving Medical Center, New York, New York, United Kingdom.ORCID 0000-0001-6302-8834
Paul MuntnerDepartment of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Columbia University Irving Medical Center · USUniversity of Alabama at Birmingham · USKaiser Permanente · USJichi Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLess than 50% of non-Hispanic Asian adults taking antihypertensive medication have controlled blood pressure.

methodsWe compared non-persistence and low adherence to antihypertensive medication between non-Hispanic Asian and other race/ethnicity groups among US adults ≥66 years who initiated antihypertensive medication between 2011 and 2018 using a 5% random sample of Medicare beneficiaries (non-Hispanic Asian, n = 2,260; non-Hispanic White, n = 56,000; non-Hispanic Black, n = 5,792; Hispanic, n = 4,212; and Other, n = 1,423). Non-persistence was defined as not having antihypertensive medication available to take in the last 90 of 365 days following treatment initiation. Low adherence was defined as having antihypertensive medication available to take on <80% of the 365 days following initiation.

resultsIn 2011-2012, 2013-2014, 2015-2016 and 2017-2018, the proportion of non-Hispanic Asian Medicare beneficiaries with non-persistence was 29.1%, 25.6%, 25.4% and 26.7% (p-trend = 0.381), respectively, and the proportion with low adherence was 58.1%, 54.2%, 53.4% and 51.6%, respectively (p-trend = 0.020). In 2017-2018, compared with non-Hispanic Asian beneficiaries, non-persistence was less common among non-Hispanic White beneficiaries (risk ratio 0.74 [95%CI, 0.64-0.85]), non-Hispanic Black beneficiaries (0.80 [95%CI 0.68-0.94]) and those reporting Other race/ethnicity (0.68 [95%CI, 0.54-0.85]) but not among Hispanic beneficiaries (1.04 [95%CI, 0.88-1.23]). Compared to non-Hispanic Asian beneficiaries, non-Hispanic White beneficiaries and beneficiaries reporting Other race/ethnicity were less likely to have low adherence to antihypertensive medication (relative risk 0.78 [95%CI 0.72-0.84] and 0.84 [95%CI 0.74-0.95], respectively); there was no association for non-Hispanic Black or Hispanic beneficiaries.

conclusionsNon-persistence and low adherence to antihypertensive medication were more common among older non-Hispanic Asian than non-Hispanic White adults.

Indexed as

Antihypertensive AgentsHypertensionAdultAgedEthnicityHumansMedicareMedication AdherenceUnited StatesAntihypertensive Agents

Identifiers

PMID38507422
PMCPMC10954118
OpenAlexW4392983525

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.