Evidence map›Paper›PMID 38507271›Full record

ReviewCancer reports (Hoboken, N.J.)2024

New insights on testicular cancer prevalence with novel diagnostic biomarkers and therapeutic approaches.

Kadry M Sadek, Hazem Y AbdEllatief, Sahar F E Mahmoud, Athanasios Alexiou, Marios Papadakis, Marwan Al-Hajeili, Hebatallah M Saad, Gaber El-Saber Batiha

Abstract readReview
In one paragraph

Review in Cancer reports (Hoboken, N.J.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Exosomal ncRNAs in reproductive cancers†.Biology of reproduction · 2025
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kadry M SadekDepartment of Biochemistry, Faculty of Veterinary Medicine, Damanhour University, Abadiyyat Damanhur, Egypt.
Hazem Y AbdEllatiefDepartment of Biochemistry, Faculty of Veterinary Medicine, Damanhour University, Abadiyyat Damanhur, Egypt.
Sahar F E MahmoudDepartment of Histology, Faculty of Veterinary Medicine, Damanhour University, Abadiyyat Damanhur, Egypt.
Athanasios AlexiouUniversity Centre for Research and Development, Chandigarh University, Mohali, Punjab, India.ORCID 0000-0002-2206-7236
Marios PapadakisDepartment of Surgery II, University Hospital Witten-Herdecke, Wuppertal, Germany.
Marwan Al-HajeiliDepartment of Medicine, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.
Hebatallah M SaadDepartment of Pathology, Faculty of Veterinary Medicine, Matrouh University, Marsa Matruh, Egypt.ORCID 0000-0001-9555-7300
Gaber El-Saber BatihaDepartment of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour, Egypt.ORCID 0000-0002-7817-425X

Funding

University of Witten-Herdecke Germany
6 · The paper itself

Abstract

backgroundTesticular cancer (TC), comprising merely 1% of male neoplasms, holds the distinction of being the most commonly encountered neoplasm among young males. RECENT

findingsMost cases of testicular neoplasms can be classified into two main groups, namely germ cell tumors representing approximately 95% of the cases, and sex cord-stromal tumors accounting for about 5% of the cases. Moreover, its prevalence is on the rise across the globe. TC is a neoplastic condition characterized by a favorable prognosis. The advent of cisplatin-based chemotherapeutic agents in the latter part of the 1970s has led to a significant enhancement in the 5-year survival rate, which presently surpasses 95%. Given that TC is commonly detected before reaching the age of 40, it can be anticipated that these individuals will enjoy an additional 40-50 years of life following successful treatment. The potential causes of TC are multifactorial and related to different pathologies. Accurate identification is imperative to guarantee the utmost efficacious and suitable therapy. To a certain degree, this can be accomplished through the utilization of blood examinations for neoplastic indicators; nonetheless, an unequivocal diagnosis necessitates an evaluation of the histological composition of a specimen via a pathologist.

conclusionTC is multifactorial and has various pathologies, therefore this review aimed to revise the prenatal and postnatal causes as well as novel diagnostic biomarkers and the therapeutic strategies of TC.

Indexed as

Neoplasms, Germ Cell and EmbryonalTesticular NeoplasmsAdultBiomarkersHumansMaleMiddle AgedPrevalenceBiomarkerscancerdiagnosisgerm cellmaleseminomatestistreatment

Identifiers

PMID38507271
PMCPMC10953835

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.