Evidence map›Paper›PMID 38507269›Full record

ArticleAdvanced healthcare materials2024

Localized Surface Plasmon Resonance-Enhanced Photocatalytic Antibacterial of In Situ Sprayed 0D/2D Heterojunction Composite Hydrogel for Treating Diabetic Wound.

Zhengao Wang, Wei Li, Youzhun Fan, Cairong Xiao, Zhifeng Shi, Yunbing Chang, Guoyan Liang, Chengli Liu, Zurong Zhu, Peng Yu and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced healthcare materials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Recent Development of Fibrous Hydrogels: Properties, Applications and Perspectives.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Zhengao WangSchool of Materials Science and Engineering, South China University of Technology, Guangzhou, 510006, P. R. China.
Wei LiSchool of Materials Science and Engineering, South China University of Technology, Guangzhou, 510006, P. R. China.
Youzhun FanSchool of Materials Science and Engineering, South China University of Technology, Guangzhou, 510006, P. R. China.
Cairong XiaoSchool of Materials Science and Engineering, South China University of Technology, Guangzhou, 510006, P. R. China.
Zhifeng ShiNational Engineering Research Center for Tissue Restoration and Reconstruction, South China University of Technology, Guangzhou, 510006, P. R. China.
Yunbing ChangDepartment of Orthopedics, Guangdong Provincial People's Hospital, Guangzhou, 510080, P.R. China.
Guoyan LiangDepartment of Orthopedics, Guangdong Provincial People's Hospital, Guangzhou, 510080, P.R. China.
Chengli LiuSchool of Materials Science and Engineering, South China University of Technology, Guangzhou, 510006, P. R. China.
Zurong ZhuSchool of Materials Science and Engineering, South China University of Technology, Guangzhou, 510006, P. R. China.
Peng YuSchool of Materials Science and Engineering, South China University of Technology, Guangzhou, 510006, P. R. China.
Xuebin YangBiomaterials and Tissue Engineering Group, School of Dentistry, University of Leeds, Leeds, LS97TF, UK.
Zhiguo SongSchool of Materials Science and Engineering, Kunming University of Science and Technology, Kunming, 650093, P.R. China.
Chengyun NingSchool of Materials Science and Engineering, South China University of Technology, Guangzhou, 510006, P. R. China.ORCID 0000-0003-3293-4716

Funding

Fundamental Research Funds for the Central Universities 2022ZYGXZR049National Key Research and Development Program of China 2021YFC2400402National Key Research and Development Program of China 2022YFC2406000National Natural Science Foundation of China 51932002National Natural Science Foundation of China 52101285National Natural Science Foundation of China U22A20160Royal Society IEC∖NSFC∖191344
6 · The paper itself

Abstract

Chronic diabetic wounds pose significant challenges due to uncontrolled bacterial infections, prolonged inflammation, and impaired angiogenesis. The rapid advancement of photo-responsive antibacterial therapy shows promise in addressing these complex issues, particularly utilizing 2D heterojunction materials, which offer unique properties. Herein, an in situ sprayed Bi/BiOCl 0D/2D heterojunction composite fibrin gel with the characteristics of rapid formation and effective near-infrared activation is designed for the treatment of non-healing diabetes-infected wounds. The sprayed composite gel can provide protective shielding for skin tissues and promote endothelial cell proliferation, vascularization, and angiogenesis. The Bi/BiOCl 0D/2D heterojunction, with its localized surface plasmon resonance (LSPR), can overcome the wide bandgap limitation of BiOCl, enhancing the generation of local heat and reactive oxygen species under near-infrared irradiation. This facilitates bacterial elimination and reduced inflammation, supporting the accelerated healing of diabetes-infected wounds. This study underscores the potential of LSPR-enhanced heterojunctions as advanced wound therapies for chronic diabetic wounds.

Indexed as

Anti-Bacterial AgentsHydrogelsSurface Plasmon ResonanceWound HealingAnimalsCatalysisDiabetes Mellitus, ExperimentalHumansMiceReactive Oxygen SpeciesAnti-Bacterial AgentsHydrogelsReactive Oxygen Speciesantibacterialdiabetic woundsheterojunctionlocalized surface plasmon resonanceNIR‐activable

Identifiers

PMID38507269
PMCPMC11582506

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.