Evidence map›Paper›PMID 38507264›Full record

ArticleCancer reports (Hoboken, N.J.)2024

Does diabetes affect breast cancer survival?

Ross Lawrenson, Chunhuan Lao, James Stanley, Andrea Teng, Marion Kuper-Hommel, Ian Campbell, Jeremy Krebs, Dianne Sika-Paotonu, Jonathan Koea, Ineke Meredith and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cancer reports (Hoboken, N.J.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Diabetes and cancer: glucose control impact on survival and tumor outcomes.Reviews in endocrine & metabolic disorders · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Does diabetes affect breast cancer survival?Cancer reports (Hoboken, N.J.) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Ross LawrensonMedical Research Centre, The University of Waikato, Hamilton, New Zealand.ORCID 0000-0003-0437-8839
Chunhuan LaoMedical Research Centre, The University of Waikato, Hamilton, New Zealand.ORCID 0000-0002-2319-8916
James StanleyDepartment of Public Health, University of Otago, Wellington, New Zealand.
Andrea TengDepartment of Public Health, University of Otago, Wellington, New Zealand.
Marion Kuper-HommelMedical Oncology, Waikato Hospital, Hamilton, New Zealand.
Ian CampbellDepartment of Surgery, Faculty of Health Sciences, The University of Auckland, Auckland, New Zealand.
Jeremy KrebsDepartment of Medicine, University of Otago, Wellington, New Zealand.
Dianne Sika-PaotonuDean's Department UOW & Division of Health Sciences, University of Otago, New Zealand.
Jonathan KoeaGeneral Surgery, Waitakere Hospital, Auckland, New Zealand.
Ineke MeredithGeneral Surgery, Wakefield Hospital, Wellington, New Zealand.
Jason GurneyDepartment of Public Health, University of Otago, Wellington, New Zealand.
University of Otago · NZUniversity of Auckland · NZClinical Trials New Zealand · NZWaikato Hospital · NZWaikato Regional Council · NZWakefield Hospital · NZ

Funding

Health Research Council of New Zealand 21/068
6 · The paper itself

Abstract

objectivesThe objective of this study is to investigate the influence of diabetes on breast cancer-specific survival among women with breast cancer in Aotearoa/New Zealand.

methodsThis study included women diagnosed with invasive breast cancer between 2005 and 2020, with their information documented in the Te Rēhita Mate Ūtaetae-Breast Cancer Foundation National Register. Breast cancer survival curves for women with diabetes and those without diabetes were generated using the Kaplan-Meier method. The hazard ratio (HR) of breast cancer-specific mortality for women with diabetes compared to women without diabetes was estimated using the Cox proportional hazards model.

resultsFor women with diabetes, the 5-year and 10-year of cancer-specific survival were 87% (95% CI: 85%-88%) and 79% (95% CI: 76%-81%) compared to 89% (95% CI: 89%-90%) and 84% (95% CI: 83%-85%) for women without diabetes. The HR of cancer-specific mortality for patients with diabetes compared to those without diabetes was 0.99 (95% CI: 0.89-1.11) after adjustment for patient demographics, tumor characteristics, and treatments. Age at cancer diagnosis and cancer stage had the biggest impact on the survival difference between the two groups. When stratified by cancer stage, the cancer-specific mortality between the two groups was similar.

conclusionsWhile differences in survival have been identified for women with diabetes when compared to women without diabetes, these are attributable to age and the finding that women with diabetes tend to present with more advanced disease at diagnosis. We did not find any difference in survival between the two groups due to differences in treatment.

Indexed as

Breast NeoplasmsDiabetes MellitusFemaleHumansNeoplasm StagingNew ZealandProportional Hazards Modelsbreast cancercause of deathdiabetesmortalitysurvival

Identifiers

PMID38507264
PMCPMC10953831
OpenAlexW4392985890

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.