Evidence map›Paper›PMID 38506785›Full record

ArticleAmerican journal of preventive medicine2024

Changes in Age Distribution and Maternal Mortality in a Subset of the U.S., 2014-2021.

Zachary H Hughes, Lydia M Hughes, Xiaoning Huang, Lucia C Petito, William A Grobman, Sadiya S Khan

Abstract read
In one paragraph

Article in American journal of preventive medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Contribution of Maternal Age to Increasing Severe Maternal Morbidity During Birth and Up to 1 Year Postpartum.Women's health issues : official publication of the Jacobs Institute of Women's Health
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zachary H HughesDepartment of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Lydia M HughesDepartment of Obstetrics and Gynecology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Xiaoning HuangDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Lucia C PetitoDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
William A GrobmanDepartment of Obstetrics and Gynecology, The Ohio State University College of Medicine, Columbus, Ohio.
Sadiya S KhanDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Division of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois. Electronic address: s-khan-1@northwestern.edu.

Funding

PRegnancy OuTcomEs and subclinical Cardiovascular disease sTudy: (PROTECT)R01HL161514 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Sadiya Sana Khan · 2022 to 2026
$3.3M
2-Generation Interventions to Improve Cardiovascular Health in Indiana and Illinois Through Home Visiting (2-NOURISH)UG3HL163121 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DAVIS, MATTHEW M, KHAN, SADIYA SANA · 2022 to 2023
$1.5M
NHLBI NIH HHS R01 HL161514NHLBI NIH HHS UG3 HL163121
6 · The paper itself

Abstract

introductionThis study aimed to determine the association between changes in age distribution and maternal mortality rates (MMR) in a subset of the United States between 2014 and 2021.

methodsA serial cross-sectional analysis of birthing individuals aged 15-44 years from 2014 to 2021 was performed. States that had not adopted the pregnancy checkbox as of 2014 were excluded from the primary analysis. A significant inflection point in MMR was identified in 2019 with the Joinpoint Regression Program, so all analyses were stratified: 2014-2019 and 2019-2021. The Kitagawa decomposition was applied to quantify the contribution from (1) changes in age distribution and (2) changes in age-specific MMR (ASMR) to total MMR. Data analysis occurred between 2022 and 2023.

resultsFrom 2014 to 2021, the mean (standard deviation) age of birthing individuals changed from 28.3 (5.8) to 29.4 (5.7) years. The MMR (95% CI) increased significantly from 16.5 (15.8-18.5) to 18.9 (17.4-20.5) per 100,000 live births from 2014 to 2019 with acceleration in MMR to 31.8 (30.0-33.8) by 2021. The change in maternal age distribution contributed to 36% of the total change in the MMR from 2014 to 2019 and 4% from 2019 to 2021. Age-specific MMR components increased significantly for those aged 25-29 years and 30-34 years from 2014 to 2019. All 5-year age strata except the 15-19 year old group saw increases in age-specific MMR from 2019 to 2021.

conclusionsMMR increased significantly from 2014 to 2021 with rapid increase after 2019. However, older age of birthing individuals explained only a minority of the increased MMR in both periods. The greatest contribution to MMR arose from increases in age-specific MMR.

Indexed as

Maternal MortalityAdolescentAdultAge DistributionCross-Sectional StudiesFemaleHumansPregnancyUnited StatesYoung Adult

Identifiers

PMID38506785
PMCPMC11193619

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.