Evidence map›Paper›PMID 38506780›Full record

Observational studyMayo Clinic proceedings2024

County Rurality and Incidence and Prevalence of Diagnosed Diabetes in the United States.

Sagar B Dugani, Brian D Lahr, Hui Xie, Michelle M Mielke, Kent R Bailey, Adrian Vella

Abstract readObservational Study
In one paragraph

Observational study in Mayo Clinic proceedings, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sagar B DuganiDivision of Hospital Internal Medicine, Mayo Clinic, Rochester, MN; Division of Health Care Delivery Research, Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN. Electronic address: dugani.chandrasagar@mayo.edu.
Brian D LahrDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, MN.
Hui XieCenters for Disease Control and Prevention, Atlanta, GA.
Michelle M MielkeDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, MN; Department of Epidemiology and Prevention, Wake Forest University School of Medicine, Winston-Salem, NC.
Kent R BaileyDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, MN.
Adrian VellaDivision of Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic, Rochester, MN.

Funding

The regulation of fasting glucose metabolism in people with and without prediabetesR01DK078646 · NIDDK · MAYO CLINIC ROCHESTER · PI Adrian Vella · 2007 to 2026
$8.7M
Glucagon suppression and diabetes-associated variation in TCF7L2R01DK116231 · NIDDK · MAYO CLINIC ROCHESTER · PI Adrian Vella · 2017 to 2026
$5.4M
The effect of endogenous GLP-1 secretion on islet function in vivoR01DK126206 · NIDDK · MAYO CLINIC ROCHESTER · PI Adrian Vella · 2020 to 2026
$4.0M
Rural Patient Risks and Exposures for Diabetes ConTrol (Rural PREDICT)K23MD016230 · NIMHD · MAYO CLINIC ROCHESTER · PI DUGANI, CHANDRASAGAR · 2021 to 2025
$763k
NIDDK NIH HHS R01 DK078646NIDDK NIH HHS R01 DK116231NIDDK NIH HHS R01 DK126206NIMHD NIH HHS K23 MD016230
6 · The paper itself

Abstract

objectiveTo examine differences in the incidence and prevalence of diagnosed diabetes by county rurality. PATIENTS AND

methodsThis observational, cross-sectional study used US Centers for Disease Control and Prevention data from 2004 through 2019 for county estimates of incidence and prevalence of diagnosed diabetes. County rurality was based on 6 levels (large central metro counties [most urban] to noncore counties [most rural]). Weighted least squares regression was used to relate rurality with diabetes incidence rates (IRs; per 1000 adults) and prevalence (percentage) in adults aged 20 years or older after adjusting for county-level sociodemographic factors (eg, food environment, health care professionals, inactivity, obesity).

resultsOverall, in 3148 counties and county equivalents, the crude IR and prevalence of diabetes were highest in noncore counties. In age and sex ratio-adjusted models, the IR of diabetes increased monotonically with increasing rurality (P<.001), whereas prevalence had a weak, nonmonotonic but statistically significant increase (P=.002). Further adjustment for sociodemographic factors including food environment, health care professionals, inactivity, and obesity attenuated differences in incidence across rurality levels, and reversed the pattern for prevalence (prevalence ratios [vs large central metro] ranged from 0.98 [95% CI, 0.97 to 0.99] for large fringe metro to 0.94 [95% CI, 0.93 to 0.96] for noncore). In region-stratified analyses adjusted for sociodemographic factors including inactivity and obesity, increasing rurality was inversely associated with incidence in the Midwest and West only and inversely associated with prevalence in all regions.

conclusionThe crude incidence and prevalence of diagnosed diabetes increased with increasing county rurality. After accounting for sociodemographic factors including food environment, health care professionals, inactivity, and obesity, county rurality showed no association with incidence and an inverse association with prevalence. Therefore, interventions targeting modifiable sociodemographic factors may reduce diabetes disparities by region and rurality.

Indexed as

Diabetes MellitusRural PopulationAdultAgedCross-Sectional StudiesFemaleHumansIncidenceMaleMiddle AgedPrevalenceUnited StatesYoung Adult

Identifiers

PMID38506780
PMCPMC11222038

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.