Evidence map›Paper›PMID 38506737›Full record

ArticleEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology2024

Comparison of two self-expanding transcatheter heart valves for degenerated surgical bioprostheses: the AVENGER multicentre registry.

Won-Keun Kim, Moritz Seiffert, Andreas Rück, David M Leistner, Henryk Dreger, Hendrik Wienemann, Matti Adam, Helge Möllmann, Johannes Blumenstein, Clemens Eckel and 38 more

Abstract readMulticenter Study
In one paragraph

Article in EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

48 authors.

Won-Keun KimDepartment of Cardiology, Kerckhoff Heart Center, Bad Nauheim, Germany and DZHK (German Centre for Cardiovascular Research), Partner Site Rhein/Main, Germany.
Moritz SeiffertDepartment of Cardiology, University Heart and Vascular Center Hamburg, University Hospital Hamburg-Eppendorf (UKE), Hamburg, Germany and DZHK (German Centre for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, Germany.
Andreas RückDepartment of Cardiology, Karolinska University Hospital, Stockholm, Sweden.
David M LeistnerUniversity Heart & Vascular Center Frankfurt, Frankfurt, Germany and DZHK (German Centre for Cardiovascular Research), Partner Site Rhein/Main, Germany.
Henryk DregerDepartment of Cardiology, Angiology and Intensive Care Medicine, Deutsches Herzzentrum der Charite (DHZC), Berlin, Germany.
Hendrik WienemannClinic III for Internal Medicine, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.
Matti AdamClinic III for Internal Medicine, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.
Helge MöllmannDepartment of Cardiology, St. Johannes-Hospital, Dortmund, Germany.
Johannes BlumensteinDepartment of Cardiology, St. Johannes-Hospital, Dortmund, Germany.
Clemens EckelDepartment of Cardiology, St. Johannes-Hospital, Dortmund, Germany.
Andrea BuonoCardiovascular Department, Interventional Cardiology Unit, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy.
Diego MaffeoCardiovascular Department, Interventional Cardiology Unit, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy.
Antonio MessinaDepartment of Cardiothoracic Surgery, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy and Operative Unit of Cardiac Surgery, Poliambulanza Foundation Ospital, Brescia, Italy.
Andreas HolzamerUniversity Hospital of Regensburg, Medical Center, Regensburg, Germany.
Samuel SossallaDepartment of Cardiology, Kerckhoff Heart Center, Bad Nauheim, Germany and DZHK (German Centre for Cardiovascular Research), Partner Site Rhein/Main, Germany.
Giuliano CostaDivision of Cardiology, AOU Policlinico G. Rodolico-San Marco, Catania, Italy.
Marco BarbantiUniversità degli Studi Di Enna "Kore", Enna, Italy.
Silvia MottaDivision of Cardiology, AOU Policlinico G. Rodolico-San Marco, Catania, Italy.
Corrado TamburinoDivision of Cardiology, AOU Policlinico G. Rodolico-San Marco, Catania, Italy.
Ina von der HeideDepartment of Cardiology, University Heart and Vascular Center Hamburg, University Hospital Hamburg-Eppendorf (UKE), Hamburg, Germany and DZHK (German Centre for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, Germany.
Julius GlasmacherDepartment of Cardiology, Angiology and Intensive Care Medicine, Deutsches Herzzentrum der Charite (DHZC), Berlin, Germany.
Mohammad SherifDepartment of Cardiology, Angiology and Intensive Care Medicine, Deutsches Herzzentrum der Charite (DHZC), Berlin, Germany.
Philipp SeppeltUniversity Heart & Vascular Center Frankfurt, Frankfurt, Germany and DZHK (German Centre for Cardiovascular Research), Partner Site Rhein/Main, Germany.
Stephan FichtlschererUniversity Heart & Vascular Center Frankfurt, Frankfurt, Germany and DZHK (German Centre for Cardiovascular Research), Partner Site Rhein/Main, Germany.
Thomas WaltherUniversity Heart & Vascular Center Frankfurt, Frankfurt, Germany and DZHK (German Centre for Cardiovascular Research), Partner Site Rhein/Main, Germany.
Fausto CastriotaMaria Cecilia Hospital, GVM Care & Research, Cotignola, Italy.
Roberto NerlaMaria Cecilia Hospital, GVM Care & Research, Cotignola, Italy.
Christian FrerkerDepartment of Cardiology, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Lübeck, Germany and DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, Germany.
Tobias SchmidtDepartment of Cardiology, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Lübeck, Germany and DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, Germany.
Alexander WolfContilia Herz- und Gefäßzentrum, Elisabeth-Krankenhaus Essen, Essen, Germany.
Martin M AdamaszekContilia Herz- und Gefäßzentrum, Elisabeth-Krankenhaus Essen, Essen, Germany.
Francesco GianniniIRCCS Galeazzi Sant'Ambrogio Hospital, Milan, Italy.
Maarten VanhaverbekeDepartment of Cardiology, AZ Delta, Roeselare, Belgium.
Stefaan Van de WalleDepartment of Cardiology, AZ Delta, Roeselare, Belgium.
Francis StammenDepartment of Cardiology, AZ Delta, Roeselare, Belgium.
Stefan ToggweilerHeart Center Lucerne, Lucerner Kantonsspital, Lucerne, Switzerland.
Stephanie BrunnerHeart Center Lucerne, Lucerner Kantonsspital, Lucerne, Switzerland.
Antonio MangieriCardiocenter, IRCCS, Humanitas Research Hospital, Rozzano, Milan, Italy.
Mauro GittoDepartment of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy and IRCCS Humanitas Research Hospital, Rozzano-Milan, Italy.
Gerrit KaleschkeDepartment of Cardiology III - Adult Congenital and Valvular Heart Disease, University Hospital Muenster, Münster, Germany.
Vlasis NiniosInterbalkan European Medical Center, Thessaloniki, Greece.
Ilias NiniosInterbalkan European Medical Center, Thessaloniki, Greece.
Judith HübnerKlinik für Herz- und Kreislauferkrankungen, Deutsches Herzzentrum München, Technische Universität München, Munich, Germany and DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart Alliance, Germany.
Erion XhepaKlinik für Herz- und Kreislauferkrankungen, Deutsches Herzzentrum München, Technische Universität München, Munich, Germany and DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart Alliance, Germany.
Matthias RenkerDepartment of Cardiology, Kerckhoff Heart Center, Bad Nauheim, Germany and DZHK (German Centre for Cardiovascular Research), Partner Site Rhein/Main, Germany.
Efstratios I CharitosDepartment of Cardiac Surgery, Kerckhoff Heart Center, Bad Nauheim, Germany.
Michael JonerKlinik für Herz- und Kreislauferkrankungen, Deutsches Herzzentrum München, Technische Universität München, Munich, Germany and DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart Alliance, Germany.
Tobias RheudeKlinik für Herz- und Kreislauferkrankungen, Deutsches Herzzentrum München, Technische Universität München, Munich, Germany and DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart Alliance, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is a lack of comparative data on transcatheter aortic valve implantation (TAVI) in degenerated surgical prostheses (valve-in-valve [ViV]).

aimsWe sought to compare outcomes of using two self-expanding transcatheter heart valve (THV) systems for ViV.

methodsIn this retrospective multicentre registry, we included consecutive patients undergoing transfemoral ViV using either the ACURATE neo/neo2 (ACURATE group) or the Evolut R/PRO/PRO+ (EVOLUT group). The primary outcome measure was technical success according to Valve Academic Research Consortium (VARC)-3. Secondary outcomes were 30-day all-cause mortality, device success (VARC-3), coronary obstruction (CO) requiring intervention, rates of severe prosthesis-patient mismatch (PPM), and aortic regurgitation (AR) ≥moderate. Comparisons were made after 1:1 propensity score matching.

resultsThe study cohort comprised 835 patients from 20 centres (ACURATE n=251; EVOLUT n=584). In the matched cohort (n=468), technical success (ACURATE 92.7% vs EVOLUT 88.9%; p=0.20) and device success (69.7% vs 73.9%; p=0.36) as well as 30-day mortality (2.8% vs 1.6%; p=0.392) were similar between the two groups. The mean gradients and rates of severe PPM, AR ≥moderate, or CO did not differ between the groups. Technical and device success were higher for the ACURATE platform among patients with a true inner diameter (ID) >19 mm, whereas a true ID ≤19 mm was associated with higher device success - but not technical success - among Evolut recipients.

conclusionsViV TAVI using either ACURATE or Evolut THVs showed similar procedural outcomes. However, a true ID >19 mm was associated with higher device success among ACURATE recipients, whereas in patients with a true ID ≤19 mm, device success was higher when using Evolut.

Indexed as

Aortic Valve InsufficiencyBioprosthesisCoronary OcclusionTranscatheter Aortic Valve ReplacementCathetersHeart ValvesHumansRegistries

Identifiers

PMID38506737
PMCPMC10941672

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.