Evidence map›Paper›PMID 38506550›Full record

ArticleAntimicrobial agents and chemotherapy2024

Genomic analysis of inter-hospital transmission of vancomycin-resistant

Takaya Segawa, Kanako Masuda, Junzo Hisatsune, Kasumi Ishida-Kuroki, Yo Sugawara, Masao Kuwabara, Hideki Nishikawa, Takahiro Hiratsuka, Tatsuaki Aota, Yasuo Tao and 8 more

Open access · hybridAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Species identification and genotyping ofMicrobiology spectrum · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Clinical, genomic, and functional characterization of vancomycin-resistantFrontiers in cellular and infection microbiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 1 country.

Takaya SegawaAntimicrobial Resistance Research Center, National Institute of Infectious Diseases, Higashimurayama, Japan.ORCID 0009-0000-0248-7690
Kanako MasudaHiroshima Prefectural Center for Disease Control and Prevention, Hiroshima, Japan.ORCID 0009-0000-3164-7163
Junzo HisatsuneAntimicrobial Resistance Research Center, National Institute of Infectious Diseases, Higashimurayama, Japan.ORCID 0000-0001-9330-4203
Kasumi Ishida-KurokiAntimicrobial Resistance Research Center, National Institute of Infectious Diseases, Higashimurayama, Japan.
Yo SugawaraAntimicrobial Resistance Research Center, National Institute of Infectious Diseases, Higashimurayama, Japan.ORCID 0000-0002-9897-3905
Masao KuwabaraHiroshima Prefectural Center for Disease Control and Prevention, Hiroshima, Japan.
Hideki NishikawaHiroshima Prefectural Center for Disease Control and Prevention, Hiroshima, Japan.
Takahiro HiratsukaHiroshima Prefectural Technology Research Institute, Public Health and Environment Center, Hiroshima, Japan.
Tatsuaki AotaHiroshima City Institute of Public Health, Hiroshima, Japan.
Yasuo TaoHiroshima City Public Health Center, Hiroshima, Japan.
Yoshimi IwahashiHiroshima City Public Health Center, Hiroshima, Japan.
Kuniko UedaHiroshima City Public Health Center, Hiroshima, Japan.
Kaori MaeHiroshima City Medical Association Clinical Laboratory, Hiroshima, Japan.
Ken MasumotoHiroshima City Medical Association Clinical Laboratory, Hiroshima, Japan.
Hiroki KitagawaProject Research Center for Nosocomial Infectious Diseases, Hiroshima University, Hiroshima, Japan.
Hitoshi KomatsuzawaProject Research Center for Nosocomial Infectious Diseases, Hiroshima University, Hiroshima, Japan.ORCID 0000-0002-9094-7649
Hiroki OhgeProject Research Center for Nosocomial Infectious Diseases, Hiroshima University, Hiroshima, Japan.
Motoyuki SugaiAntimicrobial Resistance Research Center, National Institute of Infectious Diseases, Higashimurayama, Japan.ORCID 0000-0001-9252-7739
Hiroshima University · JPHiroshima Prefectural Hospital · JPNational Institute of Infectious Diseases · JP

Funding

Health and Labor Sciences Research Grant 21KA1004Japan Agency for Medical Research and Development (AMED) 22fk0108604j0002
6 · The paper itself

Abstract

Outbreaks caused by vancomycin-resistant enterococci that transcend jurisdictional boundaries are occurring worldwide. This study focused on a vancomycin-resistant enterococcus outbreak that occurred between 2018 and 2021 across two cities in Hiroshima, Japan. The study involved genetic and phylogenetic analyses using whole-genome sequencing of 103 isolates of vancomycin-resistant enterococci to identify the source and transmission routes of the outbreak. Phylogenetic analysis was performed using core genome multilocus sequence typing and core single-nucleotide polymorphisms; infection routes between hospitals were inferred using BadTrIP. The outbreak was caused by

Indexed as

Disease OutbreaksEnterococcus faeciumGram-Positive Bacterial InfectionsMultilocus Sequence TypingPhylogenyPlasmidsVancomycin-Resistant EnterococciWhole Genome SequencingAnti-Bacterial AgentsBacterial ProteinsCarbon-Oxygen LigasesCross InfectionGenome, BacterialHospitalsHumansJapanAnti-Bacterial AgentsBacterial ProteinsCarbon-Oxygen LigasesVanA ligase, BacteriaVancomycinEnterococcus faecium ST80genomic analysismultilocus sequence typingoutbreakvanAvancomycin-resistant enterococci

Identifiers

PMID38506550
PMCPMC11064488
OpenAlexW4392997465

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.