Evidence map›Paper›PMID 38506426›Full record

ReviewCell transplantation

Platelet Concentrates Preconditioning of Mesenchymal Stem Cells and Combined Therapies: Integrating Regenerative Strategies for Enhanced Clinical Applications.

Xu-Huan Li, Han-Xi Xiao, Zu-Xiu Wang, Xin-Rong Tang, Xue-Feng Yu, Yong-Ping Pan

Open access · goldAbstract readReview
In one paragraph

Review in Cell transplantation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. The contribution of probiotics to combined cellular therapy in skin wound healing in diabetic rats.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2025
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xu-Huan LiThe 4th Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Han-Xi XiaoThe 4th Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Zu-Xiu WangThe 4th Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Xin-Rong TangThe 4th Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Xue-Feng YuThe 4th Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.ORCID 0000-0003-2520-5881
Yong-Ping PanThe 4th Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Nanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This article presents a comprehensive review of the factors influencing the efficacy of mesenchymal stem cells (MSCs) transplantation and its association with platelet concentrates (PCs). It focuses on investigating the impact of PCs' composition, the age and health status of platelet donors, application methods, and environmental factors on the outcomes of relevant treatments. In addition, it delves into the strategies and mechanisms for optimizing MSCs transplantation with PCs, encompassing preconditioning and combined therapies. Furthermore, it provides an in-depth exploration of the signaling pathways and proteomic characteristics associated with preconditioning and emphasizes the efficacy and specific effects of combined therapy. The article also introduces the latest advancements in the application of biomaterials for optimizing regenerative medical strategies, stimulating scholarly discourse on this subject. Through this comprehensive review, the primary goal is to facilitate a more profound comprehension of the factors influencing treatment outcomes, as well as the strategies and mechanisms for optimizing MSCs transplantation and the application of biomaterials in regenerative medicine, offering theoretical guidance and practical references for related research and clinical practice.

Indexed as

Mesenchymal Stem CellsMesenchymal Stem Cell TransplantationBiocompatible MaterialsProteomicsRegenerative MedicineSignal TransductionBiocompatible Materialsmesenchymal stem cellsplatelet concentratesregenerative medicine

Identifiers

PMID38506426
PMCPMC10956156
OpenAlexW4393001975

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.