Evidence map›Paper›PMID 38506305›Full record

ArticleClinical and experimental dental research2024

Evaluation of the relationship between the expression of AgNOR and Ki67 with the recurrence rate in central granulomatous giant cell lesions: A case-control.

Mina T B Dareh, Azadeh Andisheh-Tadbir, Arezoo Aghakouchakzadeh

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and experimental dental research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Mina T B DarehStudent Research Committee, School of Dentistry, Alborz University of Medical Sciences, Karaj, Iran.ORCID 0009-0002-4226-0436
Azadeh Andisheh-TadbirDepartment of Oral and Maxillofacial Pathology, School of Dentistry, Oral and Dental Disease Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.ORCID 0000-0001-5802-0512
Arezoo AghakouchakzadehDepartment of oral and maxillofacial pathology, School of Dentistry, Alborz University of Medical Science, Karaj, Iran.ORCID 0000-0001-8399-8213
Jahrom University of Medical Sciences · IRShiraz University of Medical Sciences · IR

Funding

Clinical Research Development Unit of the Dental School, Alborz University of Medical Sciences
6 · The paper itself

Abstract

objectivesGiant cell granuloma is a local nonneoplastic lesion that is divided into two categories, based on its site of occurrence: Central and peripheral giant cell granuloma. Central giant cell granuloma is an intraosseous lesion that has a tendency to recure even in surgically treated cases. Several studies have proven that there is an association between different lesions clinical behavior and their histological features. The aim of this study was to evaluate the expression of AgNOR and Ki67 in lesions with and without recurrency. MATERIAL AND

methodsFiles and records of 35 patients who had been histologically diagnosed with central giant cell granuloma were investigated. Histological features were studied after performing AgNOR staining and Ki67 marker. The data were analyzed by chi-square, Fisher, and T-test.

resultsAcquired data indicated that the count of AgNOR staining and Ki67 marker was significantly higher in lesions with recurrency than the lesions with no recurrency. The same results were attained from Ki67 intensity.

conclusionThe current study indicated that AgNOR staining and Ki67 marker have prognostic value in predicting recurrency of central giant cell granuloma lesions.

Indexed as

Antigens, NuclearGranuloma, Giant CellCase-Control StudiesGiant CellsHumansKi-67 AntigenAntigens, NuclearKi-67 Antigennucleolar organizer region associated proteinsAgNORcentral giant cell granulomaKi67recurrence

Identifiers

PMID38506305
PMCPMC10952119
OpenAlexW4393004600

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.