Evidence map›Paper›PMID 38505692›Full record

ArticlePNAS nexus2024

Natural soda lakes provide compatible conditions for RNA and membrane function that could have enabled the origin of life.

Zachary R Cohen, Dian Ding, Lijun Zhou, Saurja DasGupta, Sebastian Haas, Kimberly P Sinclair, Zoe R Todd, Roy A Black, Jack W Szostak, David C Catling

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PNAS nexus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. On an RNA-Membrane Protogenome.Life (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Zachary R CohenDepartment of Chemistry, University of Washington, Seattle, WA 98195, USA.ORCID https://orcid.org/0000-0002-1257-623X
Dian DingDepartment of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.ORCID https://orcid.org/0000-0001-9046-7816
Lijun ZhouDepartment of Biochemistry and Biophysics and Penn Institute for RNA Innovation, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID https://orcid.org/0000-0002-0393-4787
Saurja DasGuptaDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA.ORCID https://orcid.org/0000-0002-9064-9131
Sebastian HaasAstrobiology Program, University of Washington, Seattle, WA 98195, USA.ORCID https://orcid.org/0000-0001-6705-0449
Kimberly P SinclairAstrobiology Program, University of Washington, Seattle, WA 98195, USA.ORCID https://orcid.org/0000-0001-6261-4591
Zoe R ToddAstrobiology Program, University of Washington, Seattle, WA 98195, USA.ORCID https://orcid.org/0000-0001-6116-4285
Roy A BlackDepartment of Chemistry, University of Washington, Seattle, WA 98195, USA.ORCID https://orcid.org/0000-0002-3914-5747
Jack W SzostakHoward Hughes Medical Institute, Department of Chemistry, University of Chicago, Chicago, IL 60637, USA.ORCID https://orcid.org/0000-0003-4131-1203
David C CatlingAstrobiology Program, University of Washington, Seattle, WA 98195, USA.ORCID https://orcid.org/0000-0001-5646-120X
University of Washington · USHarvard University · USHoward Hughes Medical Institute · USUniversity of Notre Dame · USUniversity of Pennsylvania · USUniversity of Wisconsin–Madison · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The origin of life likely occurred within environments that concentrated cellular precursors and enabled their co-assembly into cells. Soda lakes (those dominated by Na

Indexed as

membraneprotocellribozymeRNA

Identifiers

PMID38505692
PMCPMC10949909
OpenAlexW4392953623

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.