Evidence map›Paper›PMID 38505532›Full record

ArticleJBMR plus2024

Loss of the auxiliary α

Madison M Kelly, Karan Sharma, Christian S Wright, Xin Yi, Perla C Reyes Fernandez, Aaron T Gegg, Taylor A Gorrell, Megan L Noonan, Ahmed Baghdady, Jacob A Sieger and 9 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JBMR plus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 6 institutions in 3 countries.

Madison M KellyDepartment of Physical Therapy, School of Health and Human Sciences, Indiana University, Indianapolis, IN 46202, United States.
Karan SharmaDepartment of Physical Therapy, School of Health and Human Sciences, Indiana University, Indianapolis, IN 46202, United States.
Christian S WrightDepartment of Physical Therapy, School of Health and Human Sciences, Indiana University, Indianapolis, IN 46202, United States.
Xin YiDepartment of Physical Therapy, School of Health and Human Sciences, Indiana University, Indianapolis, IN 46202, United States.
Perla C Reyes FernandezDepartment of Physical Therapy, School of Health and Human Sciences, Indiana University, Indianapolis, IN 46202, United States.
Aaron T GeggDepartment of Physical Therapy, School of Health and Human Sciences, Indiana University, Indianapolis, IN 46202, United States.
Taylor A GorrellDepartment of Physical Therapy, School of Health and Human Sciences, Indiana University, Indianapolis, IN 46202, United States.
Megan L NoonanDepartment of Medical and Molecular Genetics, Indiana University, Indianapolis, IN 46202, United States.
Ahmed BaghdadyCollege of Osteopathic Medicine, Marian University, Indianapolis, IN 46222, United States.
Jacob A SiegerCollege of Osteopathic Medicine, Marian University, Indianapolis, IN 46222, United States.
Annette C DolphinDepartment of Neuroscience, Physiology and Pharmacology, University College of London, Gower Street, London WC1E 6BT, United Kingdom.
Stuart J WardenDepartment of Physical Therapy, School of Health and Human Sciences, Indiana University, Indianapolis, IN 46202, United States.
Padmini DeosthaleIndiana Center for Musculoskeletal Health, Indiana University, Indianapolis, IN 46202, United States.
Lilian I PlotkinIndiana Center for Musculoskeletal Health, Indiana University, Indianapolis, IN 46202, United States.
Uma SankarIndiana Center for Musculoskeletal Health, Indiana University, Indianapolis, IN 46202, United States.
Julia M HumCollege of Osteopathic Medicine, Marian University, Indianapolis, IN 46222, United States.
Alexander G RoblingIndiana Center for Musculoskeletal Health, Indiana University, Indianapolis, IN 46202, United States.
Mary C Farach-CarsonDepartment of Diagnostic & Biomedical Sciences, University of Texas Health Science Center at Houston School of Dentistry, Houston, TX 77054, United States.
William R ThompsonDepartment of Physical Therapy, School of Health and Human Sciences, Indiana University, Indianapolis, IN 46202, United States.
Indiana University – Purdue University Indianapolis · USIndiana University Health · USMarian University - Indiana · USIndiana University · USThe University of Texas Health Science Center at Houston · USUniversity College London · GB

Funding

Indiana Clinical and Translational Sciences InstituteUL1TR001108 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI DENNE, SCOTT C., SHEKHAR, ANANTHA · 2013 to 2017
$23.3M
Osteocyte Mechanotransduction and the Gabapentin-Sensitive Matrix-Channel Tethering ComplexR01AR074473 · NIAMS · INDIANA UNIVERSITY INDIANAPOLIS · PI THOMPSON, WILLIAM ROY · 2018 to 2023
$2.8M
CaMKK2 Inhibition as a Dual-Action Bone Anabolic and Anti-Catabolic Therapy in OsteoporosisR01AR068332 · NIAMS · INDIANA UNIVERSITY INDIANAPOLIS · PI SANKAR, UMA · 2015 to 2019
$2.1M
Regulation of Skeletal Development and Mechanosensitivity by the α2δ1 Auxiliary Voltage Sensitive Calcium Channel SubunitF32AR074893 · NIAMS · INDIANA UNIVERSITY INDIANAPOLIS · PI WRIGHT, CHRISTIAN STEPHEN · 2019 to 2021
$182k
NCATS NIH HHS UL1 TR001108NIAMS NIH HHS F32 AR074893NIAMS NIH HHS R01 AR068332NIAMS NIH HHS R01 AR074473Wellcome Trust
6 · The paper itself

Abstract

Voltage-sensitive calcium channels (VSCCs) influence bone structure and function, including anabolic responses to mechanical loading. While the pore-forming (α

Indexed as

bone formationloadingmechanotransductionvoltage-sensitive calcium channelα2δ1 subunit

Identifiers

PMID38505532
PMCPMC10945727
OpenAlexW4390690712

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.