Evidence map›Paper›PMID 38505530›Full record

ArticleJBMR plus2024

Staphylococcus aureus Panton-Valentine Leukocidin worsens acute implant-associated osteomyelitis in humanized BRGSF mice.

Marloes I Hofstee, Claudia Siverino, Motoo Saito, Himanshu Meghwani, James Tapia-Dean, Samson Arveladze, Maria Hildebrand, Javier Rangel-Moreno, Martijn Riool, Stephan Zeiter and 3 more

Open access · goldAbstract read
In one paragraph

Article in JBMR plus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Overcoming Immune Evasion inACS infectious diseases · 2025
    Review
  4. Article
  5. bioRxiv : the preprint server for biology · 2025
    Article
  6. Article
  7. The virulence toolkit of Staphylococcus aureus: a comprehensive review of toxin diversity, molecular mechanisms, and clinical implications.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Review
  8. Methicillin-sensitiveMicrobial genomics · 2025
    Article
  9. Article
  10. Immune Checkpoint Molecules as Biomarkers ofbioRxiv : the preprint server for biology · 2024
    Article
  11. Humanized Mouse Models of Bacterial Infections.Antibiotics (Basel, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 5 countries.

Marloes I HofsteeAO Research Institute Davos, 7270 Davos, Switzerland.
Claudia SiverinoAO Research Institute Davos, 7270 Davos, Switzerland.
Motoo SaitoCenter for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY 14642, United States.
Himanshu MeghwaniCenter for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY 14642, United States.
James Tapia-DeanAO Research Institute Davos, 7270 Davos, Switzerland.
Samson ArveladzeAO Research Institute Davos, 7270 Davos, Switzerland.
Maria HildebrandAO Research Institute Davos, 7270 Davos, Switzerland.
Javier Rangel-MorenoDivision of Allergy, Immunology and Rheumatology, Department of Medicine, University of Rochester Medical Center, Rochester, NY 14620, United States.
Martijn RioolDepartment of Medical Microbiology and Infection Prevention, Amsterdam UMC, Amsterdam institute for Infection and Immunity, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Stephan ZeiterAO Research Institute Davos, 7270 Davos, Switzerland.
Sebastian A J ZaatDepartment of Medical Microbiology and Infection Prevention, Amsterdam UMC, Amsterdam institute for Infection and Immunity, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
T Fintan MoriartyAO Research Institute Davos, 7270 Davos, Switzerland.
Gowrishankar MuthukrishnanCenter for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY 14642, United States.ORCID https://orcid.org/0000-0001-7521-6154
AO Foundation · CHUniversity of Rochester Medical Center · USAmsterdam University Medical Centers · NLUniversity Hospital Regensburg · DE

Funding

Rochester Resource-Based Center for Bone, Muscle and Orthopaedic Research (ROCSTARR) (Overall Application)P30AR069655 · NIAMS · UNIVERSITY OF ROCHESTER · PI Edward M. Schwarz · 2016 to 2026
$7.8M
NIAMS NIH HHS P30 AR069655
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Humanized miceneutrophilsosteomyelitisPVLstaphylococcus aureus

Identifiers

PMID38505530
PMCPMC10945728
OpenAlexW4390547339

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.