Evidence map›Paper›PMID 38505527›Full record

ArticleJBMR plus2024

Mer tyrosine kinase regulates bone metabolism, and its deficiency partially ameliorates periodontitis- and ovariectomy-induced bone loss in mice.

Ka-Young Ryu, Nitin Kumar Pokhrel, Hye-Jin Jung, Hyo Jeong Kim, Jiwon Seok, Tae-Young Kim, Hyung Joon Kim, Ji Hye Lee, Jae-Young Kim, Yong-Gun Kim and 1 more

Open access · goldAbstract read
In one paragraph

Article in JBMR plus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. MicroRNA-127-3p Inhibits In Vitro Osteogenesis and Dampens Trauma-Induced Heterotopic Ossification In Vivo.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Ka-Young RyuDepartment of Biochemistry, School of Dentistry, Kyungpook National University, Daegu 41940, Korea.
Nitin Kumar PokhrelDepartment of Biochemistry, School of Dentistry, Kyungpook National University, Daegu 41940, Korea.
Hye-Jin JungDepartment of Biochemistry, School of Dentistry, Kyungpook National University, Daegu 41940, Korea.
Hyo Jeong KimDepartment of Biochemistry, School of Dentistry, Kyungpook National University, Daegu 41940, Korea.
Jiwon SeokDepartment of Biochemistry, School of Dentistry, Kyungpook National University, Daegu 41940, Korea.
Tae-Young KimDepartment of Biochemistry, School of Dentistry, Kyungpook National University, Daegu 41940, Korea.
Hyung Joon KimDepartment of Oral Physiology, School of Dentistry, Pusan National University, Yangsan 50612, Korea.
Ji Hye LeeDepartment of Oral Pathology, School of Dentistry, Pusan National University, Yangsan 50612, Korea.
Jae-Young KimDepartment of Biochemistry, School of Dentistry, Kyungpook National University, Daegu 41940, Korea.ORCID https://orcid.org/0000-0002-6752-5683
Yong-Gun KimDepartment of Periodontology, School of Dentistry, Kyungpook National University, Daegu 41940, Korea.
Youngkyun LeeDepartment of Biochemistry, School of Dentistry, Kyungpook National University, Daegu 41940, Korea.ORCID https://orcid.org/0000-0001-9049-6908
Daegu Health College · KRBritish Society of Periodontology · GBPusan National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone homeostasis is maintained by tightly coordinated activities of bone-forming osteoblasts and bone-resorbing osteoclasts. In the present report, the role of Mer tyrosine kinase (MerTK) in bone metabolism was investigated. The expression of MerTK decreased upon BMP2 stimulation of osteoblast precursors. The femurs of

Indexed as

bone metabolismosteoblastsosteoclastsovariectomyperiodontitis

Identifiers

PMID38505527
PMCPMC10945713
OpenAlexW4390574858

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.