Evidence map›Paper›PMID 38505174›Full record

ArticleCritical care explorations2024

Alcohol Withdrawal Severity Measures for Identifying Patients Requiring High-Intensity Care.

Daniel C To, Tessa L Steel, Kyle A Carey, Cara J Joyce, Elizabeth M Salisbury-Afshar, Dana P Edelson, Anoop Mayampurath, Matthew M Churpek, Majid Afshar

Open access · goldAbstract read
In one paragraph

Article in Critical care explorations, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Dexmedetomidine in The Treatment of Toxicologic Conditions in The Emergency Department: A Dual-Center Retrospective Observational Cohort Study.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2026
    Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Daniel C ToDepartment of Medicine, University of Wisconsin-Madison, Madison, WI.
Tessa L SteelDepartment of Medicine, University of Washington, Seattle, WA.
Kyle A CareyDepartment of Medicine, University of Chicago, Chicago, IL.
Cara J JoyceDepartment of Public Health Sciences, Loyola University Chicago, Maywood, IL.
Elizabeth M Salisbury-AfsharDepartment of Family Medicine and Community Health, University of Wisconsin-Madison, Madison, WI.
Dana P EdelsonDepartment of Medicine, University of Chicago, Chicago, IL.
Anoop MayampurathDepartment of Medicine, University of Wisconsin-Madison, Madison, WI.
Matthew M ChurpekDepartment of Medicine, University of Wisconsin-Madison, Madison, WI.
Majid AfsharDepartment of Medicine, University of Wisconsin-Madison, Madison, WI.
University of Wisconsin–Madison · USUniversity of Chicago · USLoyola University Chicago · USUniversity of Washington · USUniversity of Wisconsin Health · US

Funding

Data Driven Strategies for Substance Misuse Identification in Hospitalized PatientsR01DA051464 · NIDA · UNIVERSITY OF WISCONSIN-MADISON · PI Majid Afshar · 2020 to 2026
$4.5M
Improving the Safety of Treatment for Hospitalized Patients with Alcohol Withdrawal SyndromeK23AA030588 · NIAAA · UNIVERSITY OF WASHINGTON · PI Tessa Lynne Steel · 2022 to 2026
$940k
NIAAA NIH HHS K23 AA030588NIDA NIH HHS R01 DA051464
6 · The paper itself

Abstract

objectivesAlcohol withdrawal syndrome (AWS) may progress to require high-intensity care. Approaches to identify hospitalized patients with AWS who received higher level of care have not been previously examined. This study aimed to examine the utility of Clinical Institute Withdrawal Assessment Alcohol Revised (CIWA-Ar) for alcohol scale scores and medication doses for alcohol withdrawal management in identifying patients who received high-intensity care.

designA multicenter observational cohort study of hospitalized adults with alcohol withdrawal.

settingUniversity of Chicago Medical Center and University of Wisconsin Hospital. PATIENTS: Inpatient encounters between November 2008 and February 2022 with a CIWA-Ar score greater than 0 and benzodiazepine or barbiturate administered within the first 24 hours. The primary composite outcome was patients who progressed to high-intensity care (intermediate care or ICU).

interventionsNone. MAIN

resultsAmong the 8742 patients included in the study, 37.5% (

conclusionsNeither CIWA-Ar scores nor medication dose cutoff points were effective measures for identifying patients with alcohol withdrawal who received high-intensity care. Research studies for examining outcomes in patients who deteriorate with AWS will require better methods for cohort identification.

Indexed as

alcohol use disorderbenzodiazepinesinpatientsintensive care unitssubstance withdrawal syndrome

Identifiers

PMID38505174
PMCPMC10950191
OpenAlexW4392906118

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.