Evidence map›Paper›PMID 38505118›Full record

ArticleAngewandte Chemie (Weinheim an der Bergstrasse, Germany)2022

One-Pot Biocatalytic In Vivo Methylation-Hydroamination of Bioderived Lignin Monomers to Generate a Key Precursor to L-DOPA.

James L Galman, Fabio Parmeggiani, Lisa Seibt, William R Birmingham, Nicholas J Turner

Open access · hybridAbstract read
In one paragraph

Article in Angewandte Chemie (Weinheim an der Bergstrasse, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

James L GalmanDepartment of Chemistry University of Manchester Manchester Institute of Biotechnology 131 Princess Street M1 7DN Manchester UK.ORCID 0000-0003-2076-2806
Fabio ParmeggianiDepartment of Chemistry University of Manchester Manchester Institute of Biotechnology 131 Princess Street M1 7DN Manchester UK.ORCID 0000-0001-5861-9269
Lisa SeibtDepartment of Chemistry University of Manchester Manchester Institute of Biotechnology 131 Princess Street M1 7DN Manchester UK.ORCID 0000-0002-8230-5371
William R BirminghamDepartment of Chemistry University of Manchester Manchester Institute of Biotechnology 131 Princess Street M1 7DN Manchester UK.ORCID 0000-0002-8880-5502
Nicholas J TurnerDepartment of Chemistry University of Manchester Manchester Institute of Biotechnology 131 Princess Street M1 7DN Manchester UK.ORCID 0000-0002-8708-0781
University of Manchester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Electron-rich phenolic substrates can be derived from the depolymerisation of lignin feedstocks. Direct biotransformations of the hydroxycinnamic acid monomers obtained can be exploited to produce high-value chemicals, such as α-amino acids, however the reaction is often hampered by the chemical autooxidation in alkaline or harsh reaction media. Regioselective

Indexed as

Amino AcidsBiocatalysisCircular EconomyCofactor RegenerationProtein Engineering

Identifiers

PMID38505118
PMCPMC10947412
OpenAlexW4200002401

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.