Evidence map›Paper›PMID 38505008›Full record

ArticleJournal of thoracic disease2024

Artificial intelligence (AI)-assisted chest computer tomography (CT) insights: a study on intensive care unit (ICU) admittance trends in 78 coronavirus disease 2019 (COVID-19) patients.

Rudolf Bumm, Paolo Zaffino, Andras Lasso, Raúl San José Estépar, Steven Pieper, Jakob Wasserthal, Maria Francesca Spadea, Tsogyal Latshang, Nadine Kawel-Boehm, Adrian Wäckerlin and 4 more

Open access · diamondAbstract read
In one paragraph

Article in Journal of thoracic disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 5 countries.

Rudolf BummDepartment of Thoracic Surgery, Cantonal Hospital of Graubünden, Chur, Switzerland.
Paolo ZaffinoDepartment of Experimental and Clinical Medicine, University "Magna Graecia" of Catanzaro, Catanzaro, Italy.
Andras LassoLaboratory for Percutaneous Surgery, Queen's University, Kingston, Canada.
Raúl San José EstéparDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Steven PieperIsomics Inc., Cambridge, Massachusetts, USA.
Jakob WasserthalClinic of Radiology & Nuclear Medicine, University Hospital Basel, Basel, Switzerland.
Maria Francesca SpadeaInstitute of Biomedical Engineering, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany.
Tsogyal LatshangDepartment of Pneumonology, Cantonal Hospital of Graubünden, Chur, Switzerland.
Nadine Kawel-BoehmDepartment of Radiology, Cantonal Hospital of Graubünden, Chur, Switzerland.
Adrian WäckerlinDepartment of Intensive Care Medicine, Cantonal Hospital of Graubünden, Chur, Switzerland.
Raphael WernerDepartment of Thoracic Surgery, Cantonal Hospital of Graubünden, Chur, Switzerland.
Gabriela HässigDepartment of Thoracic Surgery, Cantonal Hospital of Graubünden, Chur, Switzerland.
Markus FurrerDepartment of Thoracic Surgery, Cantonal Hospital of Graubünden, Chur, Switzerland.
Ron KikinisDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Kantonsspital Graubünden · CHBrigham and Women's Hospital · USKarlsruhe Institute of Technology · DEMagna Graecia University · ITQueen's University · CAUniversity Hospital of Basel · CH

Funding

CT and CXR Phenotyping Platform for Assessing COVID-19 Susceptibility and SeverityR21LM013670 · NLM · BRIGHAM AND WOMEN'S HOSPITAL · PI SAN JOSE ESTEPAR, RAUL · 2021 to 2022
$428k
NLM NIH HHS R21 LM013670
6 · The paper itself

Abstract

Background: The global coronavirus disease 2019 (COVID-19) pandemic has posed substantial challenges for healthcare systems, notably the increased demand for chest computed tomography (CT) scans, which lack automated analysis. Our study addresses this by utilizing artificial intelligence-supported automated computer analysis to investigate lung involvement distribution and extent in COVID-19 patients. Additionally, we explore the association between lung involvement and intensive care unit (ICU) admission, while also comparing computer analysis performance with expert radiologists' assessments. Methods: A total of 81 patients from an open-source COVID database with confirmed COVID-19 infection were included in the study. Three patients were excluded. Lung involvement was assessed in 78 patients using CT scans, and the extent of infiltration and collapse was quantified across various lung lobes and regions. The associations between lung involvement and ICU admission were analysed. Additionally, the computer analysis of COVID-19 involvement was compared against a human rating provided by radiological experts. Results: The results showed a higher degree of infiltration and collapse in the lower lobes compared to the upper lobes (P<0.05). No significant difference was detected in the COVID-19-related involvement of the left and right lower lobes. The right middle lobe demonstrated lower involvement compared to the right lower lobes (P<0.05). When examining the regions, significantly more COVID-19 involvement was found when comparing the posterior Conclusions: The findings suggest that the extent of lung involvement, particularly in the lower lobes, dorsal lungs, and lower half of the lungs, may be associated with the need for ICU admission in patients with COVID-19. Computer analysis showed a high correlation with expert rating, highlighting its potential utility in clinical settings for assessing lung involvement. This information may help guide clinical decision-making and resource allocation during ongoing or future pandemics. Further studies with larger sample sizes are warranted to validate these findings.

Indexed as

artificial intelligence-supported computed tomography computer analysis (AI-supported CT computer analysis)clinical decision-makingCoronavirus disease 2019 (COVID-19)COVID lung involvementforecast of intensive care unit admission (forecast of ICU admission)

Identifiers

PMID38505008
PMCPMC10944742
OpenAlexW4392244678

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.