Evidence map›Paper›PMID 38504998›Full record

ReviewAngewandte Chemie (Weinheim an der Bergstrasse, Germany)2022

Challenges and Breakthroughs in Selective Amide Activation.

Minghao Feng, Haoqi Zhang, Nuno Maulide

Abstract readReview
In one paragraph

Review in Angewandte Chemie (Weinheim an der Bergstrasse, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Minghao FengFaculty of Chemistry Institute of Organic Chemistry University of Vienna Währinger Straße 38 1090 Vienna Austria.
Haoqi ZhangFaculty of Chemistry Institute of Organic Chemistry University of Vienna Währinger Straße 38 1090 Vienna Austria.
Nuno MaulideFaculty of Chemistry Institute of Organic Chemistry University of Vienna Währinger Straße 38 1090 Vienna Austria.ORCID 0000-0003-3643-0718

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In contrast to ketones and carboxylic esters, amides are classically seen as comparatively unreactive members of the carbonyl family, owing to their unique structural and electronic features. However, recent decades have seen the emergence of research programmes focused on the selective activation of amides under mild conditions. In the past four years, this area has continued to rapidly develop, with new advances coming in at a fast pace. Several novel activation strategies have been demonstrated as effective tools for selective amide activation, enabling transformations that are at once synthetically useful and mechanistically intriguing. This Minireview comprises recent advances in the field, highlighting new trends and breakthroughs in what could be called a new age of amide activation.

Indexed as

Amide ActivationAmide FunctionalisationElectrophilic ActivationSynthetic MethodsTransition-Metal Catalysis

Identifiers

PMID38504998
PMCPMC10947092

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.