Evidence map›Paper›PMID 38504389›Full record

ArticleThe Korean journal of pain2024

Current understanding of nociplastic pain.

Yeong-Min Yoo, Kyung-Hoon Kim

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in The Korean journal of pain, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06957873 (Evaluation of the Relationship Between Craniovertebral Angle and Fibromyalgia Symptom Severity), which is not on this map. Cited by 43 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 2 pooled it
13.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06957873 recruitingnot on this mapstarted 2025, after this paper: background citation

Evaluation of the Relationship Between Craniovertebral Angle and Fibromyalgia Symptom Severity

TypeobservationalSponsorAnkara Training and Research HospitalRan2025 to 2026Enrolled134ConditionsCraniovertebral Angle, Fibromyalgia Syndrome
3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Pooled it
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  6. C-low threshold mechanoreceptors: a novel target for health-tech in an increasingly touch-deprived world.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2026
    Review
  7. Neuropathic pain versus restless legs syndrome: distinct and combined effects on balance and walking performance in multiple sclerosis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Yeong-Min YooDepartment of Anesthesia and Pain Medicine, School of Medicine, Pusan National University, Yangsan, Korea.ORCID https://orcid.org/0000-0003-3536-0447
Kyung-Hoon KimDepartment of Anesthesia and Pain Medicine, School of Medicine, Pusan National University, Yangsan, Korea.ORCID https://orcid.org/0000-0003-3925-8917
Pusan National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nociplastic pain by the "International Association for the Study of Pain" is defined as pain that arises from altered nociception despite no clear evidence of nociceptive or neuropathic pain. Augmented central nervous system pain and sensory processing with altered pain modulation are suggested to be the mechanism of nociplastic pain. Clinical criteria for possible nociplastic pain affecting somatic structures include chronic regional pain and evoked pain hypersensitivity including allodynia with after-sensation. In addition to possible nociplastic pain, clinical criteria for probable nociplastic pain are pain hypersensitivity in the region of pain to non-noxious stimuli and presence of comorbidity such as generalized symptoms with sleep disturbance, fatigue, or cognitive problems with hypersensitivity of special senses. Criteria for definitive nociplastic pain is not determined yet. Eight specific disorders related to central sensitization are suggested to be restless leg syndrome, chronic fatigue syndrome, fibromyalgia, temporomandibular disorder, migraine or tension headache, irritable bowel syndrome, multiple chemical sensitivities, and whiplash injury; non-specific emotional disorders related to central sensitization include anxiety or panic attack and depression. These central sensitization pain syndromes are overlapped to previous functional pain syndromes which are unlike organic pain syndromes and have emotional components. Therefore, nociplastic pain can be understood as chronic altered nociception related to central sensitization including both sensory components with nociceptive and/or neuropathic pain and emotional components. Nociplastic pain may be developed to explain unexplained chronic pain beyond tissue damage or pathology regardless of its origin from nociceptive, neuropathic, emotional, or mixed pain components.

Indexed as

Central Nervous System SensitizationChronic PainEmotionsHyperalgesiaHypersensitivityNeuralgiaNeuronal PlasticityNociceptionNociceptive Pain

Identifiers

PMID38504389
PMCPMC10985487
OpenAlexW4393015293

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.