Evidence map›Paper›PMID 38504112›Full record

ArticleScientific reports2024

Enriched atlas of lncRNA and protein-coding genes for the GRCg7b chicken assembly and its functional annotation across 47 tissues.

Fabien Degalez, Mathieu Charles, Sylvain Foissac, Haijuan Zhou, Dailu Guan, Lingzhao Fang, Christophe Klopp, Coralie Allain, Laetitia Lagoutte, Frédéric Lecerf and 4 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 3 countries.

Fabien DegalezPEGASE, INRAE, Institut Agro, 35590, Saint Gilles, France.
Mathieu CharlesINRAE, BioinfOmics, GenoToul Bioinformatics facility, Sigenae, Université Fédérale de Toulouse, 31326, Castanet-Tolosan, France.
Sylvain FoissacGenPhySE, Université de Toulouse, INRAE, ENVT, 31326, Castanet-Tolosan, France.
Haijuan ZhouUniversity of California Davis, Davis, USA.
Dailu GuanUniversity of California Davis, Davis, USA.
Lingzhao FangAarhus University, Aarhus, Denmark.
Christophe KloppINRAE, BioinfOmics, GenoToul Bioinformatics facility, Sigenae, Université Fédérale de Toulouse, 31326, Castanet-Tolosan, France.
Coralie AllainPEGASE, INRAE, Institut Agro, 35590, Saint Gilles, France.
Laetitia LagouttePEGASE, INRAE, Institut Agro, 35590, Saint Gilles, France.
Frédéric LecerfPEGASE, INRAE, Institut Agro, 35590, Saint Gilles, France.
Hervé AcloqueINRAE, AgroParisTech, GABI, Paris-Saclay University, 78350, Jouy-en-Josas, France.
Elisabetta GiuffraINRAE, AgroParisTech, GABI, Paris-Saclay University, 78350, Jouy-en-Josas, France.
Frédérique PitelGenPhySE, Université de Toulouse, INRAE, ENVT, 31326, Castanet-Tolosan, France.
Sandrine LagarriguePEGASE, INRAE, Institut Agro, 35590, Saint Gilles, France. sandrine.lagarrigue@institut-agro.fr.
Institut Agro Rennes-Angers · FRAgroParisTech · FRÉcole Nationale Vétérinaire de Toulouse · FRUniversity of California, Davis · USAarhus University · DKInstitut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gene atlases for livestock are steadily improving thanks to new genome assemblies and new expression data improving the gene annotation. However, gene content varies across databases due to differences in RNA sequencing data and bioinformatics pipelines, especially for long non-coding RNAs (lncRNAs) which have higher tissue and developmental specificity and are harder to consistently identify compared to protein coding genes (PCGs). As done previously in 2020 for chicken assemblies galgal5 and GRCg6a, we provide a new gene atlas, lncRNA-enriched, for the latest GRCg7b chicken assembly, integrating "NCBI RefSeq", "EMBL-EBI Ensembl/GENCODE" reference annotations and other resources such as FAANG and NONCODE. As a result, the number of PCGs increases from 18,022 (RefSeq) and 17,007 (Ensembl) to 24,102, and that of lncRNAs from 5789 (RefSeq) and 11,944 (Ensembl) to 44,428. Using 1400 public RNA-seq transcriptome representing 47 tissues, we provided expression evidence for 35,257 (79%) lncRNAs and 22,468 (93%) PCGs, supporting the relevance of this atlas. Further characterization including tissue-specificity, sex-differential expression and gene configurations are provided. We also identified conserved miRNA-hosting genes with human counterparts, suggesting common function. The annotated atlas is available at gega.sigenae.org.

Indexed as

RNA, Long NoncodingAnimalsChickensHumansMolecular Sequence AnnotationSequence Analysis, RNATranscriptomeRNA, Long NoncodingChickenCo-expressionGene atlasGenome annotationLong non coding RNAsmiRNATissue specificity

Identifiers

PMID38504112
PMCPMC10951430
OpenAlexW4392949890

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.