ArticleNature medicine2024
Heterogeneity and predictors of the effects of AI assistance on radiologists.
Article in Nature medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
92 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Magnetic Resonance Imaging-Based Artificial Intelligence in Predicting Prostate Cancer Biochemical Recurrence: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2026Pooled it
- Artificial intelligence (AI) in radiological paediatric fracture assessment: an updated systematic review.European radiology · 2025Pooled it
- Artificial intelligence assistance narrows the experience gap in endoscopic reporting of gastric lesions: a prospective clinical trial.Surgical endoscopy · 2026Trial
- Artificial Intelligence Efficacy as a Function of Trainee Interpreter Proficiency: Lessons from a Randomized Controlled Trial.AJNR. American journal of neuroradiology · 2024Trial
- Evaluation of standardized DICOM labels assigned by a hybrid AI tool and its impact on radiologists' reading times.European radiology · 2026Article
- AI for Health Care Quality and Patient Safety: Scoping Review of Diagnostic, Predictive, and Decision Support Applications.Journal of medical Internet research · 2026Article
- Automated Extraction of Postoperative Cancer Recurrence and Metastasis From Computed Tomography (CT) Reports: Semisupervised Deep Learning Study.JMIR medical informatics · 2026Article
- FUO-PETMamba: a pet maximum-intensity-projection-based artificial intelligence framework for aetiological classification of fever of unknown origin with multicentre validation.European journal of nuclear medicine and molecular imaging · 2026Article
- Integration of artificial intelligence and multi-omics for precision medicine.Functional & integrative genomics · 2026Review
- Human-AI Interaction With AI-Assisted Tumor Overlays in Pediatric Whole-Body Magnetic Resonance Imaging: Exploratory Reader Study.JMIR human factors · 2026Article
- Multimodal Assessment of Tissue Response After Thyroid Radiofrequency Ablation: Clinical, Imaging, Histopathological and Molecular Insights.Journal of clinical medicine · 2026Article
- Retrieval-Augmented Generation in Radiology: A Scoping Review of Architectures, Imaging Applications, and Directions for Equitable Deployment.Journal of imaging informatics in medicine · 2026Review
- Clinical fluorescent probes: mechanisms, advantages and inspirations.Chemical science · 2026Review
- Artificial intelligence-based anatomical recognition improves surgeon decision-making during robotic gastrectomy.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2026Article
- AI home monitoring for behavioral markers of cerebrovascular disease.NPJ digital medicine · 2026Article
- Article
- Eye tracking as a tool to quantify the effects of CAD display on radiologists' interpretation of chest radiographs.European journal of radiology open · 2026Article
- Clinical Utility of AI-Enabled CT-to-MRI Translation for Degenerative Spinal Disorders: A Retrospective Reader Study.Diagnostics (Basel, Switzerland) · 2026Article
- A DeepSeek-powered AI system for automated chest radiograph interpretation in clinical practice.Nature communications · 2026Article
- DeepFAN, a transformer-based model for human-artificial intelligence collaborative assessment of incidental pulmonary nodules in CT scans: a multireader, multicase trial.Nature cancer · 2026Article
32 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on byBeyond the2025
Authors and funding
6 authors.
Funding
Abstract
The integration of artificial intelligence (AI) in medical image interpretation requires effective collaboration between clinicians and AI algorithms. Although previous studies demonstrated the potential of AI assistance in improving overall clinician performance, the individual impact on clinicians remains unclear. This large-scale study examined the heterogeneous effects of AI assistance on 140 radiologists across 15 chest X-ray diagnostic tasks and identified predictors of these effects. Surprisingly, conventional experience-based factors, such as years of experience, subspecialty and familiarity with AI tools, fail to reliably predict the impact of AI assistance. Additionally, lower-performing radiologists do not consistently benefit more from AI assistance, challenging prevailing assumptions. Instead, we found that the occurrence of AI errors strongly influences treatment outcomes, with inaccurate AI predictions adversely affecting radiologist performance on the aggregate of all pathologies and on half of the individual pathologies investigated. Our findings highlight the importance of personalized approaches to clinician-AI collaboration and the importance of accurate AI models. By understanding the factors that shape the effectiveness of AI assistance, this study provides valuable insights for targeted implementation of AI, enabling maximum benefits for individual clinicians in clinical practice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.