Evidence map›Paper›PMID 38503833›Full record

ArticleScientific reports2024

Automated body organ segmentation, volumetry and population-averaged atlas for 3D motion-corrected T2-weighted fetal body MRI.

Alena U Uus, Megan Hall, Irina Grigorescu, Carla Avena Zampieri, Alexia Egloff Collado, Kelly Payette, Jacqueline Matthew, Vanessa Kyriakopoulou, Joseph V Hajnal, Jana Hutter and 3 more

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  12. Fetuses Made Simple: Modeling and Tracking of Fetal Shape and Pose.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Alena U Uus *School of Imaging Sciences and Biomedical Engineering, King's College London, London, UK. alena.uus@kcl.ac.uk.
Megan Hall *Centre for the Developing Brain, King's College London, London, UK.
Irina GrigorescuSchool of Imaging Sciences and Biomedical Engineering, King's College London, London, UK.
Carla Avena ZampieriCentre for the Developing Brain, King's College London, London, UK.
Alexia Egloff ColladoCentre for the Developing Brain, King's College London, London, UK.
Kelly PayetteSchool of Imaging Sciences and Biomedical Engineering, King's College London, London, UK.
Jacqueline MatthewSchool of Imaging Sciences and Biomedical Engineering, King's College London, London, UK.
Vanessa KyriakopoulouCentre for the Developing Brain, King's College London, London, UK.
Joseph V HajnalSchool of Imaging Sciences and Biomedical Engineering, King's College London, London, UK.
Jana HutterSchool of Imaging Sciences and Biomedical Engineering, King's College London, London, UK.
Mary A RutherfordCentre for the Developing Brain, King's College London, London, UK.
Maria DeprezSchool of Imaging Sciences and Biomedical Engineering, King's College London, London, UK.
Lisa StoryCentre for the Developing Brain, King's College London, London, UK.

Funding

Structure and function of the placenta from implantation to delivery: a next generation MRI approachU01HD087202 · NICHD · KING'S COLLEGE LONDON · PI ALEXANDER, DANIEL, ALJABAR, PAUL · 2015 to 2015
$3.2M
NICHD NIH HHS U01 HD087202Wellcome TrustWellcome Trust 220160/Z/20/Z
6 · The paper itself

Abstract

Structural fetal body MRI provides true 3D information required for volumetry of fetal organs. However, current clinical and research practice primarily relies on manual slice-wise segmentation of raw T2-weighted stacks, which is time consuming, subject to inter- and intra-observer bias and affected by motion-corruption. Furthermore, there are no existing standard guidelines defining a universal approach to parcellation of fetal organs. This work produces the first parcellation protocol of the fetal body organs for motion-corrected 3D fetal body MRI. It includes 10 organ ROIs relevant to fetal quantitative volumetry studies. We also introduce the first population-averaged T2w MRI atlas of the fetal body. The protocol was used as a basis for training of a neural network for automated organ segmentation. It showed robust performance for different gestational ages. This solution minimises the need for manual editing and significantly reduces time. The general feasibility of the proposed pipeline was also assessed by analysis of organ growth charts created from automated parcellations of 91 normal control 3T MRI datasets that showed expected increase in volumetry during 22-38 weeks gestational age range.

Indexed as

FetusImage Processing, Computer-AssistedFemaleGestational AgeHumansMagnetic Resonance ImagingPregnancyPrenatal Care

Identifiers

PMID38503833
PMCPMC10950851

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.