Evidence map›Paper›PMID 38503771›Full record

ArticleNature communications2024

Wheat powdery mildew resistance gene Pm13 encodes a mixed lineage kinase domain-like protein.

Huanhuan Li, Wenqiang Men, Chao Ma, Qianwen Liu, Zhenjie Dong, Xiubin Tian, Chaoli Wang, Cheng Liu, Harsimardeep S Gill, Pengtao Ma and 5 more

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

  1. Fine mapping of QPm.caas-4BL.2 for adult-plant resistance to powdery mildew in wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
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  2. Article
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  5. Fine mapping and candidate gene dissection of the wheat powdery mildew resistance gene PmPBDH.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
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  14. Genetic Basis Identification of aPlants (Basel, Switzerland) · 2025
    Article
  15. Article
  16. Fine mapping of a powdery mildew resistance gene PmLF540 from wild emmer wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Article
  17. Article
  18. Article
  19. Fine mapping of a novel powdery mildew resistance gene PmDM8 derived from a cultivated emmer (Triticum dicoccum).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Huanhuan LiThe State Key Laboratory of Wheat and Maize Crop Science, College of Life Sciences, Henan Agricultural University, Zhengzhou, 450002, PR China.ORCID 0009-0007-5808-1965
Wenqiang MenThe State Key Laboratory of Wheat and Maize Crop Science, College of Life Sciences, Henan Agricultural University, Zhengzhou, 450002, PR China.ORCID 0009-0005-1248-9143
Chao MaThe State Key Laboratory of Wheat and Maize Crop Science, College of Life Sciences, Henan Agricultural University, Zhengzhou, 450002, PR China.ORCID 0009-0000-5691-8118
Qianwen LiuThe State Key Laboratory of Wheat and Maize Crop Science, College of Life Sciences, Henan Agricultural University, Zhengzhou, 450002, PR China.ORCID 0000-0001-8020-7957
Zhenjie DongCollege of Agronomy, Nanjing Agricultural University, Nanjing, 210000, PR China.
Xiubin TianInstitute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, PR China.
Chaoli WangThe State Key Laboratory of Wheat and Maize Crop Science, College of Life Sciences, Henan Agricultural University, Zhengzhou, 450002, PR China.ORCID 0009-0008-6659-045X
Cheng LiuCrop Research Institute, Shandong Academy of Agricultural Sciences, Jinan, 250000, PR China.
Harsimardeep S GillDepartment of Agronomy, Horticulture and Plant Science, South Dakota State University, Brookings, SD, 57007, USA.ORCID 0000-0002-3067-6912
Pengtao MaCollege of Life Sciences, Yantai University, Yantai, 264005, PR China.
Zhibin ZhangKey Laboratory of Molecular Epigenetics of the Ministry of Education (MOE), Northeast Normal University, Changchun, 130024, PR China.
Bao LiuKey Laboratory of Molecular Epigenetics of the Ministry of Education (MOE), Northeast Normal University, Changchun, 130024, PR China.ORCID 0000-0001-5481-1675
Yue ZhaoThe State Key Laboratory of Wheat and Maize Crop Science, College of Life Sciences, Henan Agricultural University, Zhengzhou, 450002, PR China. zhaoyue@henau.edu.cn.ORCID 0000-0001-9351-7559
Sunish K SehgalDepartment of Agronomy, Horticulture and Plant Science, South Dakota State University, Brookings, SD, 57007, USA. sunish.sehgal@sdstate.edu.ORCID 0000-0001-5644-7547
Wenxuan LiuThe State Key Laboratory of Wheat and Maize Crop Science, College of Life Sciences, Henan Agricultural University, Zhengzhou, 450002, PR China. wxliu2003@hotmail.com.ORCID 0000-0003-1227-0991

Funding

National Natural Science Foundation of China (National Science Foundation of China) 31971887National Natural Science Foundation of China (National Science Foundation of China) 32272070National Natural Science Foundation of China (National Science Foundation of China) 32372089
6 · The paper itself

Abstract

Wheat powdery mildew is one of the most destructive diseases threatening global wheat production. The wild relatives of wheat constitute rich sources of diversity for powdery mildew resistance. Here, we report the map-based cloning of the powdery mildew resistance gene Pm13 from the wild wheat species Aegilops longissima. Pm13 encodes a mixed lineage kinase domain-like (MLKL) protein that contains an N-terminal-domain of MLKL (MLKL_NTD) domain in its N-terminus and a C-terminal serine/threonine kinase (STK) domain. The resistance function of Pm13 is validated by mutagenesis, gene silencing, transgenic assay, and allelic association analyses. The development of introgression lines with significantly reduced chromosome segments of Ae. longissima encompassing Pm13 enables widespread deployment of this gene into wheat cultivars. The cloning of Pm13 may provide valuable insights into the molecular mechanisms underlying Pm13-mediated powdery mildew resistance and highlight the important roles of kinase fusion proteins (KFPs) in wheat immunity.

Indexed as

AegilopsAscomycotaDisease ResistanceGenes, PlantPlant DiseasesProtein KinasesTriticumProtein Kinases

Identifiers

PMID38503771
PMCPMC10951266

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.